Breathe Well Live Well
|
Merck's stock falls after disclosing government probe into asthma drug pricing
MarketWatch Merck & Co. Inc.'s stock dropped 1.5% in midday trade Friday, after the drug maker disclosed in a filing late Thursday that it had received a civil investigative demand from the U.S. Attorney's office. The demand requests information related to the … |
View full post on asthma – Google News
|
Studies Probe Links Between Childhood Asthma and Obesity
JAMA_ The Journal of the American Medical Association For decades, investigators have been documenting associations between obesity and asthma in adults, although the underlying mechanisms involved have remained largely unknown. Ongoing work is revealing a link in children as well and is providing new … |
View full post on asthma – Google News
| Related Articles |
Comprehensive FISH Probe Design Tool Applied to Imaging Human Immunoglobulin Class Switch Recombination.
PLoS One. 2012;7(12):e51675
Authors: Nedbal J, Hobson PS, Fear DJ, Heintzmann R, Gould HJ
Abstract
We present a web engine boosted fluorescence in-situ hybridization (webFISH) algorithm using a genome-wide sequence similarity search to design target-specific single-copy and repetitive DNA FISH probes. The webFISH algorithm featuring a user-friendly interface (http://www.webfish2.org/) maximizes the coverage of the examined sequences with FISH probes by considering locally repetitive sequences absent from the remainder of the genome. The highly repetitive human immunoglobulin heavy chain sequence was analyzed using webFISH to design three sets of FISH probes. These allowed direct simultaneous detection of class switch recombination in both immunoglobulin-heavy chain alleles in single cells from a population of cultured primary B cells. It directly demonstrated asynchrony of the class switch recombination in the two alleles in structurally preserved nuclei while permitting parallel readout of protein expression by immunofluorescence staining. This novel technique offers the possibility of gaining unprecedented insight into the molecular mechanisms involved in class switch recombination.
PMID: 23272136 [PubMed – in process]
View full post on pubmed: asthma
|
Lawmaker wants probe of EPA experiments on humans
Fox News James Inhofe, R-Okla., called it “extremely disturbing” that EPA scientists may have exposed people with conditions such as asthma and a syndrome that puts them at higher risk for heart disease and strokes to concentrated, high levels of substances … EPA's Human Experiments, Salmonella Scare and Terrorists Extradited to the U.S. |
View full post on asthma – Google News
|
Powerful lawmaker wants probe of EPA experiments on humans
Fox News called it “extremely disturbing” that EPA scientists may have exposed people with conditions such as asthma and a syndrome that puts them at higher risk for heart disease and strokes to concentrated, high levels of substances like fine particulate … |
View full post on asthma – Google News
 CBS Local |
Southfield to probe 911 response after boy, 10, dies of asthma attack
Detroit Free Press Fire Chief Keith Rowley said a large house fire that swamped the department's resources led to a 15-minute response time to the Oxley Street apartment of Xavier Joe, who was having an asthma attack. Rowley said the department prides itself on keeping … Southfield officials reviewing asthma attack response time 10-year-old Southfield boy dies from asthma attack, EMS response time blamed |
View full post on asthma – Google News
|
Shock results of probe into Darlington child asthma deaths
The Advertiser Series A SHOCK report has discovered that nearly half of child asthma deaths in a North-East town occurred in youngsters with mild or moderate forms of the illness. The results of a survey of child asthma deaths in Darlington have prompted GPs, … |
View full post on asthma – Google News
|
Shock results of probe into child asthma deaths
The Advertiser Series A SHOCK report has discovered that nearly half of child asthma deaths in a North-East town occurred in youngsters with mild or moderate forms of the illness. The results of a survey of child asthma deaths in Darlington have prompted GPs, … |
View full post on asthma – Google News
|
Shock results of probe into Darlington child asthma deaths
The Northern Echo A SHOCK report has discovered that nearly half of child asthma deaths in a North-East town occurred in youngsters with mild or moderate forms of the illness. The results of a survey of child asthma deaths in Darlington have prompted GPs, … |
View full post on asthma – Google News
|
Researchers win $1.2M grant to probe urban kids' asthma
NorthJersey.com He said a stress event such as an asthma attack normally causes the body's adrenal gland to release the hormones cortisol and epinephrine, which can help … |
View full post on asthma – Google News