Breathe Well Live Well
|
Researchers identify hCRTh2 protein as possible therapeutic target for asthma
News-Medical.net Patients with asthma have chronic lung inflammation that results in sporadic narrowing of the airways and difficulty breathing. Symptoms and severity are variable among individuals; however, the cells and inflammatory factors that trigger asthmatic … |
View full post on asthma – Google News
|
University Of Arizona Research Shows Protein Could Help Treat Asthma
KJZZ The federal Centers for Disease Control and Prevention say as of 2012 more than 25 million Americans had asthma. More than 3,600 people died from it that year. Researchers at the University of Arizona are looking to genetics as a possible new treatment. |
View full post on asthma – Google News
|
Prenatal C-reactive protein levels indicative of early-onset asthma
Healio “Asthma is a complex clinical disease that is difficult to critically assess before 6 years of age,” the researchers wrote. “Because the present study included diagnoses before 3 years of age, the nature of the disease progression might still be … |
View full post on asthma – Google News
Lung Disease News |
Targeting CCL28 Protein Structure May Help Prevent Asthma, Study Shows
Lung Disease News Asthma is a chronic inflammatory disease of the air passages characterized by airflow obstruction and with common symptoms of wheezing, coughing and shortness of breath. Currently, there is no cure for asthma and affects approximately 25 million people … |
View full post on asthma – Google News
RedOrbit |
Protein linked to viral-induced asthma
RedOrbit New research from the Medical College of Wisconsin (MCW) and the Children's Hospital of Wisconsin Research Institute has linked a specific type of protein to the development of viral-induced asthma – a discovery that could help treat the condition in … CCL28 Protein Linked To Development Of Asthma Public Release: 20-Feb-2015 Protein linked to development of asthma Protein linked to development of asthma paves way for novel therapy |
View full post on asthma – Google News
Health Aim |
CCL28 Protein Linked To Development Of Asthma
Health Aim Asthma is not an unknown disease to anyone now. In all our gathering there is someone or another who is suffering from asthma. It is estimated that around 300 million people worldwide suffer from asthma. In a very recent study published in the Journal … Protein linked to development of asthma paves way for novel therapy Public Release: 20-Feb-2015 Protein linked to development of asthma Researchers identify protein linked to asthma |
View full post on asthma – Google News
Zee News |
CCL28 protein linked to development of asthma
Science Codex Researchers have linked a specific protein to the development of post-viral infection asthma, which is the first step in generating a novel type of asthma therapy designed to prevent development of post-viral asthma in young children. Asthma is a … Public Release: 20-Feb-2015 Protein linked to development of asthma Protein tied to asthma identified |
View full post on asthma – Google News
|
Public Release: 20-Feb-2015 Protein linked to development of asthma
EurekAlert (press release) Researchers at the Medical College of Wisconsin (MCW) have linked a specific protein to the development of post-viral infection asthma, which is the first step in generating a novel type of asthma therapy designed to prevent development of post-viral … |
View full post on asthma – Google News
|
Protein linked to development of asthma
Medical Xpress Researchers at the Medical College of Wisconsin (MCW) have linked a specific protein to the development of post-viral infection asthma, which is the first step in generating a novel type of asthma therapy designed to prevent development of post-viral … |
View full post on asthma – Google News
Predictive value of C-reactive protein in response to macrolides in children with macrolide-resistant Mycoplasma pneumoniae pneumonia.
Korean J Pediatr. 2014 Apr;57(4):186-92
Authors: Seo YH, Kim JS, Seo SC, Seo WH, Yoo Y, Song DJ, Choung JT
Abstract
PURPOSE: The prevalence of macrolide-resistant Mycoplasma pneumoniae (MRMP) has increased worldwide. The aim of this study was to estimate the proportion of MRMP in a tertiary hospital in Korea, and to find potential laboratory markers that could be used to predict the efficacy of macrolides in children with MRMP pneumonia.
METHODS: A total of 95 patients with M. pneumoniae pneumonia were enrolled in this study. Detection of MRMP was based on the results of specific point mutations in domain V of the 23S rRNA gene. The medical records of these patients were reviewed retrospectively and the clinical course and laboratory data were compared.
RESULTS: The proportion of patients with MRMP was 51.6% and all MRMP isolates had the A2063G point mutation. The MRMP group had longer hospital stay and febrile period after initiation of macrolides. The levels of serum C-reactive protein (CRP) and interleukin-18 in nasopharyngeal aspirate were significantly higher in patients who did not respond to macrolide treatment. CRP was the only significant factor in predicting the efficacy of macrolides in patients with MRMP pneumonia. The area under the curve for CRP was 0.69 in receiver operating characteristic curve analysis, indicating reasonable discriminative power, and the optimal cutoff value was 40.7 mg/L.
CONCLUSION: The proportion of patients with MRMP was high, suggesting that the prevalence of MRMP is rising rapidly in Korea. Serum CRP could be a useful marker for predicting the efficacy of macrolides and helping clinicians make better clinical decisions in children with MRMP pneumonia.
PMID: 24868216 [PubMed]
View full post on pubmed: asthma