Condition: Asthma
Intervention: Other: Q-Kap
Sponsor: Stefania La Grutta, MD
Not yet recruiting – verified June 2015
View full post on ClinicalTrials.gov: asthma | received in the last 14 days
Validation Of A Questionnaire Against Clinical Assessment In The Diagnosis Of Asthma In Schoolchildren.
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Validation Of A Questionnaire Against Clinical Assessment In The Diagnosis Of Asthma In Schoolchildren.
J Asthma. 2014 Sep 18;:1-25
Authors: Hansen TE, Evjenth B, Holt J
Abstract
Abstract Aim: A questionnaire has been used repeatedly in cross sectional studies to determine the prevalence of asthma, allergic rhinoconjunctivitis (AR) and eczema among schoolchildren in Nordland County, Norway. The current study was designed to validate the questionnaire against clinical assessment as the diagnostic gold standard and to investigate the extent of possible misclassification. Methods: A subsample of 801 schoolchildren of 4150, whose parents had answered a questionnaire covering asthma and atopic diseases, underwent a detailed clinical evaluation including a standardized interview, a clinical examination, skin prick tests (SPT), blood samples, spirometry an exercise treadmill test (EIB test) and measurement of exhaled nitrogen oxide (FeNO). Results: The questionnaire had a sensitivity of 0.96 and a specificity of 0.87 for the diagnosis of asthma ever compared to clinical assessment. The overall agreement (kappa) was 0.80. After clinical assessment the prevalence of asthma ever was adjusted from 17.6 % to 16.9 % (95% CI: 15.8-18.0). The most sensitive and specific questions in identifying asthmatic children by the questionnaire were questions asking about diagnosis (‘Has the child ever had asthma?’) rather than those covering asthma symptoms such as wheeze, shortness of breath and/or cough. A positive exercise test increased the posttest probability for the asthma diagnosis only to a minimal degree. Conclusion: Based on the good agreement between the questionnaire responses and the clinical assessments, it is concluded that the questionnaire had good validity and served as a useful epidemiological tool. Detailed clinical testing added little additional information.
PMID: 25233047 [PubMed – as supplied by publisher]
View full post on pubmed: asthma
The relationship between antibiotic therapy in early childhood and the symptoms of allergy in children aged 6-8 years – the questionnaire study results.
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The relationship between antibiotic therapy in early childhood and the symptoms of allergy in children aged 6-8 years – the questionnaire study results.
Int J Occup Med Environ Health. 2012 Dec 3;
Authors: Raciborski F, Tomaszewska A, Komorowski J, Samel-Kowalik P, Bia?oszewski AZ, Artur W, Lusawa A, Szyma?ski J, Opoczy?ska D, Dru?ba M, Borowicz J, Lipiec A, Kapalczynski WJ, Samoli?ski B
Abstract
INTRODUCTION: Studies based on the ISAAC questionnaire suggest a correlation between the use of antibiotics and the prevalence of asthma and allergy in children aged 6-7 years. The number of courses of antibiotic therapy is an important factor. OBJECTIVES: To investigate the relationship between the use of antibiotics during the first years of life and the prevalence of allergy and asthma among children (aged 6-8 years) in the urban population of Poland. MATERIALS AND METHODS: A survey-based study with a self-completed questionnaire. The respondents were parents of children aged 6-8 years living in Warszawa, Poland. 1461 completed questionnaires were collected. RESULTS: Asthma was declared in 4.3% of the children. Wheezing and/or sibilant rhonchi within 12 months before the study was observed in 13.5% of the cases. Asthma medication was taken by 21.8% of the children. Allergic rhinitis was declared in 18.7% of the children. Problems with sneezing, rhinorrhea, and nasal congestion not associated with cold or fever were observed in 40.7% of the children. The analysis of the odds ratios between the use of antibiotics and the symptoms of allergic diseases revealed a clear correlation. The highest odds ratio was observed between the completion of over three courses of antibiotic therapy prior to the age of 12 months and the declaration of one of the following: asthma (OR = 5.59, 95% CI: 2.6-12.01), wheezing and/or sibilant rhonchi (OR = 4.68, 95% CI: 3.01-7.27) and taking medicines for breathlessness (OR = 5.12, 95% CI: 3.42-7.68). CONCLUSIONS: There is a direct relationship between antibiotic use in the first 3 years of life and asthma and allergy symptoms in children aged 6-8 years old.
PMID: 23212289 [PubMed – as supplied by publisher]
View full post on pubmed: asthma
Validating a questionnaire diagnosis of asthma in children using health claims … – BMC Pediatrics
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Validating a questionnaire diagnosis of asthma in children using health claims …
BMC Pediatrics Childhood asthma prevalence is widely measured by parental proxy report of physician-diagnosed asthma in questionnaires. Our objective was to validate this measure in a North American population. The 2884 study participants were a subsample of 5619 … |
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Questionnaire can help pediatricians track respiratory, asthma control – Pediatric SuperSite
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Questionnaire can help pediatricians track respiratory, asthma control
Pediatric SuperSite The Test for Respiratory and Asthma Control in Kids, or TRACK, can help pediatricians, as well as asthma specialists, monitor asthma symptoms in patients, according to researchers. Bradley Chipps, MD,of Capital Allergy and Respiratory Disease Center, … |
View full post on asthma – Google News
Questionnaire Helps Pediatricians Track Kids’ Asthma Control – Medscape
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Questionnaire Helps Pediatricians Track Kids' Asthma Control
Medscape March 4, 2011 — A short questionnaire, originally developed for use by asthma specialists, has shown for the first time it can also help pediatricians monitor control of respiratory and asthma symptoms in children younger than 5 years. … |
View full post on asthma – Google News