In NIH-funded study, researchers uncover early step in the cascade of brain events leading up to addiction

A regulatory protein best known for its role in a rare genetic brain disorder also may play a critical role in cocaine addiction, according to a recent study
in rats, funded by the National Institute on Drug Abuse (NIDA), a component of
the National Institutes of Health. The study was published today in the journal
Nature Neuroscience.

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NIH-Funded Researchers Make Progress Toward Regenerating Tissue to Replace Joints

A team of NIH-funded researchers has successfully regenerated rabbit
joints using a cutting edge process to form the joint inside the body,
or in vivo. Regenerative in vivo procedures are performed by stimulating
previously irreparable organs or tissues to heal themselves. In this
study, bioscaffolds, or three-dimensional structures made of biocompatible
and biodegradable materials in the shape of the tissue, were infused
with a protein to promote growth of the rabbit joint.

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After 40 Years, NIH-Supported Researchers Identify Possible New Treatment for Severe Vasculitis

Investigators have made a major advance in treating people with a severe form of vasculitis, anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis, a rare but devastating disease of blood vessels. In a six-month study, a new treatment strategy provided the same benefits as the current standard of care used for more than 40 years but required less frequent treatments. Early results also suggest that patients with disease relapses — typically recurrences of fever, fatigue, kidney damage, or bleeding in the lungs — respond better to the new regimen.

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