Breathe Well Live Well
|
Theravance/Glaxos Asthma Drug Under FDA Panel Review
Zacks.com We note that Theravance and partner GlaxoSmithKline (GSK – Analyst Report) are seeking to expand the label of Breo Ellipta in the U.S. for the once-daily treatment of asthma in patients aged 12 years and above. A final response from the FDA is expected … FDA advisory committee to review Theravance's BREO ELLIPTA (FF/VI) for asthma |
View full post on asthma – Google News
Lung Disease News |
Severe Asthma: New Review Highlights Areas of Diagnosis & Treatment That …
Lung Disease News pneumonectomy A new study entitled “Severe Asthma: Definition, Diagnosis and Treatment” reviews areas of concern regarding severe asthma treatment that require particular attention by clinicians. The review was published in the journal Deutsches … |
View full post on asthma – Google News
|
Ask Dr. K: Asthma requires 'action plan'
The Spokesman Review DEAR DOCTOR K: My son was recently diagnosed with asthma. His doctor wants to put together an asthma “action plan.” What is that? DEAR READER: Asthma is a complicated and serious disease. A person with asthma needs a plan for what to do at each … |
View full post on asthma – Google News
Complex interventions reduce use of urgent healthcare in adults with asthma: Systematic review with meta-regression.
Respir Med. 2014 Nov 15;
Authors: Blakemore A, Dickens C, Anderson R, Tomenson B, Woodcock A, Guthrie E
Abstract
INTRODUCTION: Asthma accounts for considerable healthcare expenditure, a large proportion of which is attributable to use of expensive urgent healthcare. This review examines the characteristics of complex interventions that reduce urgent healthcare use in adults with asthma.
METHOD: Electronic searches of MEDLINE, EMBASE, PSYCINFO, CINAHL, the British Nursing Library and the Cochrane library, from inception to January 2013 were conducted. Studies were eligible for inclusion if they: i) included adults with asthma ii) assessed the efficacy of a complex intervention using randomised controlled trial design, and iii) included a measure of urgent healthcare utilisation at follow-up. Data on participants recruited, methods, characteristics of complex interventions and the effects of the intervention on urgent healthcare use were extracted.
RESULTS: 33 independent studies were identified resulting in 39 comparisons altogether. Pooled effects indicated that interventions were associated with a reduction in urgent healthcare use (OR = 0.79, 95% CI = 0.67, 0.94). When study effects were grouped according to the components of the interventions used, significant effects were seen for interventions that included general education (OR = 0.77, 95% CI = 0.64, 0.91), skills training (OR = 0.64, 95% CI = 0.48, 0.86) and relapse prevention (OR = 0.75, 95% CI = 0.57, 0.98). In multivariate meta-regression analysis, only skills training remained significant.
CONCLUSIONS: Complex interventions reduced the use of urgent healthcare in adults with asthma by 21%. Those complex interventions including skills training, education and relapse prevention may be particularly effective in reducing the use of urgent healthcare in adults with asthma.
PMID: 25433953 [PubMed – as supplied by publisher]
View full post on pubmed: asthma
The Times (subscription) |
'Scandalous' rise in asthma deaths after NHS review
The Times (subscription) Charities say the statistics highlight an unacceptable lack of progress since an in-depth review by the Royal College of Physicians in May found that two thirds of asthma deaths could have been avoided. The national review of asthma deaths found that … |
View full post on asthma – Google News
|
FDA to review new drug application for Spiriva Respimat for asthma
Healio Boehringer Ingelheim Pharmaceuticals announced that the FDA has agreed to review its new drug application for tiotropium bromide inhalation spray for long-term maintenance of patients aged 12 years and older with asthma, according to a press release. Boehringer Ingelheim Announces U.S. Filing Acceptance of New Drug … |
View full post on asthma – Google News
|
Evanston Health Dept. program to address school-age asthma
Evanston Review Evanston Health and Human Services officials are initiating a pilot program in the coming year to address asthma in school-aged children, responding to initial survey data and hospital visits information indicating incidence of the disease may be … |
View full post on asthma – Google News
| Related Articles |
The genus Peucedanum traditional Uses, phytochemistry and Pharmacological Properties: A Review.
J Ethnopharmacol. 2014 Sep 2;
Authors: Sarkhail P
Abstract
ETHNOPHARMACOLOGICAL RELEVANCE: The genus Peucedanum (Apiaceae) comprising more than 120 species are widely distributed in Europe, Asia and Africa. The ethnopharmacologial history of this genus indicated that some extracts of aerial and underground parts of several Peucedanum species have used in folk medicine for treatment of various conditions, such as cough, cramps, pain, rheumatism, asthma and angina.
AIM OF THE REVIEW: This review focuses on ethnopharmacological uses of Peucedanum species, as well as the phytochemical, pharmacological and toxicological studies on this genus. Through this review, we intend to highlight the known and potential effects of the Peucedanum species or their isolated compounds and show which of traditional medicine uses have supported by pharmacological investigations.
METHODS: Information on the Peucedanum species collected from scientific journals, books, thesis and reports via a library and electronic search (using Google Scholar, Pubmed, Scopus, Web of Science and ScienceDirect). This review covers the available literature from 1970 to the end of September 2013.
RESULTS: Although, there are about 120 species in this genus, so far many species that have received no or little attention and the most of pharmacological studies were performed just about 20 species. Many phytochemical investigations on this genus confirmed Peucedanum species are rich in essential oils and coumarins. The present review article shows Peucedanum species have a wide spectrum of pharmacological activities that the most reported activities of Peucedanum plants come back to the presence of coumarins, flavonoids, phenolics and essential oils CONCLUSIONS: The present review confirmed some Peucedanum species have emerged as a good source of the traditional medicine for treatment of inflammation, microbial infections, cardiopulmonary diseases and provides new insights for further investigations on isolated compounds specially on praeruptorins to find novel therapeutics and drug discovery. However, for uses of Peucedanum species to prevent and treat various diseases the additional pharmacological studies to find the mechanism of action, safety and efficacy of them before starting clinical trials are required.
PMID: 25193684 [PubMed – as supplied by publisher]
View full post on pubmed: asthma
|
FDA approves GSK's Arnuity Ellipta to treat asthma in US
Pharmaceutical Business Review The US Food and Drug Administration (FDA) has approved GlaxoSmithKline's (GSK) fluticasone furoate inhalation powder, to be sold as Arnuity Ellipta, as a daily-once corticosteroid for treatment of asthma in patients aged above twelve years in the US. |
View full post on asthma – Google News
|
GPs review how well patient asthma is controlled
News-Medical.net A new Clinical e-Audit from NPS MedicineWise has been released that will help GPs review just how well patient asthma is controlled. Survey findings* released last month showed that over half of all respondents to a survey of adults with asthma said … |
View full post on asthma – Google News