Risk of Migraine in Patients With Asthma: A Nationwide Cohort Study.

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Risk of Migraine in Patients With Asthma: A Nationwide Cohort Study.

Medicine (Baltimore). 2016 Mar;95(9):e2911

Authors: Peng YH, Chen KF, Kao CH, Chen HJ, Hsia TC, Chen CH, Liao WC

Abstract
Asthma has been described as an “acephalic migraine” and “pulmonary migraine.” However, no study has investigated the temporal frequency of migraine development in patients with asthma, and the results of previous studies may be difficult to generalize.We investigated the effect of asthma on the subsequent development of migraine by using a population-based data set in Taiwan.We retrieved our study sample from the National Health Insurance Research Database. Specifically, 25,560 patients aged 12 years and older with newly diagnosed asthma were identified as the asthma group, and 102,238 sex and age-matched patients without asthma were identified as the nonasthma group. Cox proportional-hazards regression models were employed to measure the risk of migraine for the asthmatic group compared with that for the nonasthmatic group.The risk of migraine in the asthmatic group was 1.45-fold higher (95% confidence interval 1.33-1.59) than that in the nonasthmatic group after adjustment for sex, age, the Charlson comorbidity index, common medications prescribed for patients with asthma, and annual outpatient department visits. An additional stratified analysis revealed that the risk of migraine remained significantly higher in both sexes and all age groups older than 20 years.Asthma could be an independent predisposing risk factor for migraine development in adults.

PMID: 26945388 [PubMed – in process]

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Effect of smoking status on the efficacy of the SMART regimen in high risk asthma.

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Effect of smoking status on the efficacy of the SMART regimen in high risk asthma.

Respirology. 2016 Feb 21;

Authors: Pilcher J, Patel M, Reddel HK, Pritchard A, Black P, Shaw D, Holt S, Weatherall M, Beasley R

Abstract
BACKGROUND AND OBJECTIVE: The optimal management of people with asthma with a significant smoking history is uncertain. The aim of this study was to determine whether the efficacy/safety profile of single combination inhaled corticosteroid (ICS)/long acting beta-agonist (LABA) inhaler maintenance and reliever therapy is influenced by smoking status.
METHODS: We undertook secondary analyses from an open-label 24-week randomized study of 303 high risk adult asthma patients randomized to budesonide/formoterol 200/6-µg-metred dose inhaler for maintenance (two actuations twice daily) and either budesonide/formoterol 200/6-µg-metred dose inhaler one actuation (‘single ICS/LABA maintenance and reliever therapy (SMART)’ regimen) or salbutamol 100?µg 1-2 actuations for symptom relief (‘Standard’ regimen). Smoking status was classified in to three groups, as ‘current’, ‘ex’ or ‘never’, and a smoking/treatment interaction term tested for each outcome variable. The primary outcome variable was number of participants with at least one severe exacerbation.
RESULTS: There were 59 current, 97 ex and 147 never smokers included in the analyses. The smoking status/treatment interaction term was not statistically significant for any of the outcome measures. With adjustment for smoking status, the number of participants with severe exacerbations was lower with the SMART regimen (OR 0.45, 95% CI: 0.26-0.77, P?=?0.004; P value for interaction between smoking status and treatment 0.29).
CONCLUSION: We conclude that the favourable safety/efficacy profile of the SMART regimen applies to patients with high risk asthma, irrespective of smoking status.

PMID: 26897389 [PubMed – as supplied by publisher]

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Link Found Between Asthma and a Higher Risk of Abdominal Aortic Aneurysms – Lung Disease News


Lung Disease News

Link Found Between Asthma and a Higher Risk of Abdominal Aortic Aneurysms
Lung Disease News
In a new study, researchers found that recent active asthma in patients aged 50 years or older increased the risk for abdominal aortic aneurysms (AAA) and their rupture. The research article, “Asthma Associates with Human Abdominal Aortic Aneurysm and …

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Lack of asthma testing could risk the careers of young footballers – HealthCanal.com (press release) (blog)

Lack of asthma testing could risk the careers of young footballers
HealthCanal.com (press release) (blog)
Teenagers who play in elite youth football leagues could be jeopardising their health and sporting potential because they aren't getting tested for asthma early in their career, suggests Brunel University London exercise and respiratory physiologist, …

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Vitamin D levels during pregnancy did not decrease infant asthma risk – Healio


Latinos Health

Vitamin D levels during pregnancy did not decrease infant asthma risk
Healio
Women who received a high dose of vitamin D while pregnant did not achieve a statistically significant decrease in the risk for having children who developed asthma within the first 3 years of life, according to results from a randomized, double blind, …
Vitamin D Benefits in Pregnant Women Include Less Risk of Asthma in BabiesLatinos Health
Pregnant women should eat vitamin D-rich foods to reduce child's allergy riskTV3.ie
Vitamin D could reduce allergy risksiAfrica.com

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Vitamin D Benefits in Pregnant Women Include Less Risk of Asthma in Babies – Latinos Health


Latinos Health

Vitamin D Benefits in Pregnant Women Include Less Risk of Asthma in Babies
Latinos Health
Therefore, scientists have long sought to discover its potential role in asthma and allergies," the report noted. "Now, a new study has revealed a higher intake of foods containing vitamin D in pregnancy reduces the risk of childhood asthma by 20
Vitamin D could reduce allergy risksiAfrica.com

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Air pollution exposure during pregnancy linked to asthma risk – Thelakeandeswave


Thelakeandeswave

Air pollution exposure during pregnancy linked to asthma risk
Thelakeandeswave
For the study, researchers analyzed more than 65,000 children born in Vancouver from 1999 until 2002 to identify the link between asthma and their mothers' exposure to air pollution during the pregnancy. It is scientifically proved that the risk of
Air pollution increases asthma risk in babiesThe Indian Republic

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Women With Asthma May Have Higher Risk of Fertility Problems – Health.com


Health.com

Women With Asthma May Have Higher Risk of Fertility Problems
Health.com
12, 2016 (HealthDay News) — Women with asthma may take longer to get pregnant and have a lower pregnancy rate than those without the lung disease, new research suggests. The study included 245 women, aged 23 to 45, who had unexplained fertility …
Women With Asthma May Have Fertility ProblemsWebMD
Asthma linked to an increased time to pregnancy European Lung FoundationEurekAlert (press release)
Study finds women with asthma have fertility issuesFox 28

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