8 Surprising Facts About Asthma and Seasonal Allergies – U.S. News & World Report


The Independent

8 Surprising Facts About Asthma and Seasonal Allergies
U.S. News & World Report
But those obvious triggers aren't the only thing making you sneeze and rub your eyes. Ever wonder why you can't catch your breath during a thunderstorm – or why your lips itch after biting into a pear? Read on, and then prepare to wow with your asthma
Asthma and hay fever suffers can help scientists tackle conditions by sharing symptoms in #BritainBreathing appThe Independent
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Why allergy season is getting longer, more intenseCBS News
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Asthma in winter: Cold weather can trigger asthma attacks, seasonal allergies – Bel Marra Health


Bel Marra Health

Asthma in winter: Cold weather can trigger asthma attacks, seasonal allergies
Bel Marra Health
Asthma in winter: Cold weather can trigger asthma attacks, seasonal allergies Asthma in the winter can trigger asthma attacks and seasonal allergies. The cold winter air can be an asthmatic's worst nightmare as it makes it far more difficult to breathe.

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Study suggests new way to reduce seasonal asthma attacks in high-risk children – La Crosse Tribune

Study suggests new way to reduce seasonal asthma attacks in high-risk children
La Crosse Tribune
Adding targeted and short-term use of the drug omalizumab to guidelines-directed treatment just before the start of school cut in half the number of autumn asthma attacks, or exacerbations, in high-risk children. The findings are part of a clinical

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Cytokine profile of bronchoalveolar lavage fluid from a mouse model of bronchial asthma during seasonal H1N1 infection.

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Cytokine profile of bronchoalveolar lavage fluid from a mouse model of bronchial asthma during seasonal H1N1 infection.

Cytokine. 2014 Jul 3;69(2):206-210

Authors: Hasegawa S, Wakiguchi H, Okada S, Gui Kang Y, Fujii N, Hasegawa M, Hasegawa H, Ainai A, Atsuta R, Shirabe K, Toda S, Wakabayashi-Takahara M, Morishima T, Ichiyama T

Abstract
BACKGROUND: Several studies support the role of viral infections in the pathogenesis of asthma exacerbation. However, several pediatricians believe that influenza virus infection does not exacerbate bronchial asthma, except for influenza A H1N1 2009 pandemic [A(H1N1)pdm09] virus infection. We previously reported that A(H1N1)pdm09 infection possibly induces severe pulmonary inflammation or severe asthmatic attack in a mouse model of bronchial asthma and in asthmatic children. However, the ability of seasonal H1N1 influenza (H1N1) infection to exacerbate asthmatic attacks in bronchial asthma patients has not been previously reported, and the differences in the pathogenicity profiles, such as cytokine profiles, remains unclear in bronchial asthma patients after A(H1N1)pdm09 and H1N1 infections.
METHODS: The cytokine levels and viral titers in the bronchoalveolar lavage (BAL) fluid from mice with and without asthma after H1N1 infection (A/Yamagata and A/Puerto Rico strains) were compared.
RESULTS: The interleukin (IL)-6, IL-10, tumor necrosis factor (TNF)-?, IL-5, interferon (IFN)-?, IFN-?, and IFN-? levels were significantly higher in the BAL fluids from the control/H1N1 mice than from the asthmatic/H1N1 mice. The viral titers in the BAL fluid were also significantly higher in the control/H1N1mice than in the asthmatic/H1N1 mice infected with either A/Yamagata or A/Puerto Rico.
CONCLUSIONS: A(H1N1)pdm09 infection, but not H1N1 infection, can induce severe pulmonary inflammation through elevated cytokine levels in a mouse model of asthma.

PMID: 24998935 [PubMed – as supplied by publisher]

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