Study explores new approaches to prevent fall asthma exacerbations in … – News-Medical.net

Study explores new approaches to prevent fall asthma exacerbations in
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Experts from Children's Hospital Colorado (Children's Colorado) co-led a team of researchers in studying new approaches to reducing fall asthma exacerbations in pediatric patients. Their findings were released online in late October and published in

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Medical care and treatment of allergic rhinitis. A population-based cohort study based on routine healthcare utilization data.

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Medical care and treatment of allergic rhinitis. A population-based cohort study based on routine healthcare utilization data.

Allergy. 2016 Jan 8;

Authors: Schmitt J, Stadler E, Küster D, Wüstenberg EG

Abstract
BACKGROUND: Health services research on medical care and treatment of allergic rhinitis (AR) is scarce.
OBJECTIVES: To investigate the prevalence, incidence, comorbidities, and treatment of AR in a realistic setting.
METHODS: A cohort of 1,811,094 German National Health Insurance beneficiaries in 2005 was followed until 2011. To avoid misclassification, the ICD-10-code for AR (J30) had to be documented at least twice to classify patients as having AR. Descriptive statistics and logistic regression models were used to describe the burden, comorbidities, and treatment of AR.
RESULTS: A total of 111,394 patients (6.2%) had prevalent AR in 2005/2006. In another 60,145 individuals (3.3%) AR was newly diagnosed in 2007 to 2011 (incident cases). Patients with prevalent AR were three times more likely to develop asthma compared to patients without AR (age and sex-adjusted risk ratio (RR) 3.04; 95% confidence interval (95%CI) 2.98 – 3.10). Newly diagnosed recurrent depressive disorder (RR 1.61; 95%CI 1.55 – 1.68), anxiety disorder (RR 1.52; 95%CI 1.48 – 1.56) and ADHD (RR 1.21; 95%CI 1.13 – 1.29) were also related to prevalent AR. Approximately 20% of children and 36% of adults with AR were exclusively treated by general practitioners. Allergy immunotherapy (AIT) was prescribed for 16.4% of AR patients. Subcutaneous immunotherapy was most frequently used (80% of AIT).
CONCLUSIONS: This study highlights the significant burden of AR. Despite the established benefits of AIT to treat AR and prevent asthma this study suggests significant undertreatment. Future research is necessary to develop and implement adequate measures to increase guideline adherence. This article is protected by copyright. All rights reserved.

PMID: 26749452 [PubMed – as supplied by publisher]

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A Study to Assess the Safety, Tolerability and Pharmacokinetics of AZD7594 Inhaled Formulation in Healthy Japanese Men

Conditions:   Asthma;   Chronic Obstructive Pulmonary Disease (COPD)
Interventions:   Drug: AZD7594 inhalation powder (200 ?g);   Drug: AZD7594 inhalation powder (400 ?g);   Drug: AZD7594 pressurized inhalation suspension (200 ?g);   Drug: AZD7594 placebo inhalation powder;   Drug: AZD7594 placebo pressurized inhalation suspension
Sponsor:   AstraZeneca
Not yet recruiting – verified December 2015

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Study Ties Autism Risk to Prenatal Exposure to Asthma Drugs – U.S. News & World Report


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Study Ties Autism Risk to Prenatal Exposure to Asthma Drugs
U.S. News & World Report
WEDNESDAY, Jan. 6, 2016 (HealthDay News) — Children whose mothers took certain asthma drugs during pregnancy may have a slightly increased risk of autism, a new study suggests. The study, published online Jan. 6 in Pediatrics, found a connection …
Prenatal Exposure to Asthma Drugs Tied to AutismNewsmax

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