Risk of suicide for individuals reporting asthma and atopy in young adulthood: Findings from the Glasgow Alumni study.

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Risk of suicide for individuals reporting asthma and atopy in young adulthood: Findings from the Glasgow Alumni study.

Psychiatry Res. 2014 Dec 19;

Authors: Crawford AA, Galobardes B, Jeffreys M, Davey Smith G, Gunnell D

Abstract
There is emerging evidence that asthma and atopy may be associated with a higher risk of suicide. We investigated the association of asthma and atopy with mortality from suicide (n=32) in the Glasgow Alumni cohort, adjusting for the key confounders of socioeconomic position and smoking. We found no evidence of an association in our a priori atopy phenotypes with suicide, and there were insufficient suicides in the asthma phenotypes to draw any conclusions. In additional analyses, individuals reporting both eczema-urticaria and hay fever and those with family history of atopy were at higher risk of suicide. As these were secondary analyses and based on small numbers of events we cannot rule out chance findings. The lack of evidence in our main hypothesis may be due to the small number of suicides or reported associations between asthma and atopy may be confounded.

PMID: 25596956 [PubMed – as supplied by publisher]

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Relative Bioavailability Study of Two Montelukast Sodium (GW483100) 5 Milligrams (mg) Chewable Tablets and One Reference Montelukast Sodium 5 mg Chewable Tablet in Healthy Adult Subjects

Condition:   Respiratory Disorders
Interventions:   Drug: Reference Montelukast;   Drug: Test 1 Montelukast;   Drug: Test 2 Montelukast
Sponsor:   GlaxoSmithKline
Not yet recruiting – verified December 2014

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