Twin trials: How studying twins fuels research on allergies and asthma – Scope (blog)


Scope (blog)

Twin trials: How studying twins fuels research on allergies and asthma
Scope (blog)
For that reason, the Sean N. Parker Center for Allergy and Asthma Research is seeking both fraternal and identical twins to help examine the increasing incidence of food allergies and asthma around the world. In a recent article, the center profiled

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The rabbit as a model for studying lung disease and stem cell therapy.

The rabbit as a model for studying lung disease and stem cell therapy.

Biomed Res Int. 2013;2013:691830

Authors: Kamaruzaman NA, Kardia E, Kamaldin N’, Latahir AZ, Yahaya BH

Abstract
No single animal model can reproduce all of the human features of both acute and chronic lung diseases. However, the rabbit is a reliable model and clinically relevant facsimile of human disease. The similarities between rabbits and humans in terms of airway anatomy and responses to inflammatory mediators highlight the value of this species in the investigation of lung disease pathophysiology and in the development of therapeutic agents. The inflammatory responses shown by the rabbit model, especially in the case of asthma, are comparable with those that occur in humans. The allergic rabbit model has been used extensively in drug screening tests, and this model and humans appear to be sensitive to similar drugs. In addition, recent studies have shown that the rabbit serves as a good platform for cell delivery for the purpose of stem-cell-based therapy.

PMID: 23653896 [PubMed – in process]

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Wayne State, ACCESS studying asthma-pollution links in Dearborn’s heavily … – Greenfield Daily Reporter

Wayne State, ACCESS studying asthma-pollution links in Dearborn's heavily
Greenfield Daily Reporter
A Dearborn-based nonprofit social services agency is working with Wayne State University to study asthma in the Detroit's suburb's heavily industrial south end. The Detroit university and the Arab American Center for Community and Economic Social

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