Breathe Well Live Well
Condition: Asthma
Interventions: Drug: Mepolizumab 100mg SC; Drug: Albuterol/salbutamol MDIs; Drug: Omalizumab
Sponsor: GlaxoSmithKline
Not yet recruiting – verified January 2016
View full post on ClinicalTrials.gov: asthma | received in the last 14 days
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Inflammatory on and off switch identified for allergic asthma and COPD
EurekAlert (press release) Bethesda, MD—Japanese researchers have made a new step toward understanding why—and how to stop—runaway inflammation for both chronic obstructive pulmonary disorder (COPD) and allergic asthma. In a new report appearing in the August 2013 … |
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Inflammatory on and off switch identified for allergic asthma and COPD
Science Codex Bethesda, MD—Japanese researchers have made a new step toward understanding why—and how to stop—runaway inflammation for both chronic obstructive pulmonary disorder (COPD) and allergic asthma. In a new report appearing in the August 2013 … |
View full post on asthma – Google News
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Inflammation switch for allergic asthma, COPD found in leukotriene receptors
ScienceBlog.com (blog) Japanese researchers have made a new step toward understanding why—and how to stop—runaway inflammation for both chronic obstructive pulmonary disorder (COPD) and allergic asthma. In a new report appearing in the August 2013 issue of The … |
View full post on asthma – Google News
| Related Articles |
Comprehensive FISH Probe Design Tool Applied to Imaging Human Immunoglobulin Class Switch Recombination.
PLoS One. 2012;7(12):e51675
Authors: Nedbal J, Hobson PS, Fear DJ, Heintzmann R, Gould HJ
Abstract
We present a web engine boosted fluorescence in-situ hybridization (webFISH) algorithm using a genome-wide sequence similarity search to design target-specific single-copy and repetitive DNA FISH probes. The webFISH algorithm featuring a user-friendly interface (http://www.webfish2.org/) maximizes the coverage of the examined sequences with FISH probes by considering locally repetitive sequences absent from the remainder of the genome. The highly repetitive human immunoglobulin heavy chain sequence was analyzed using webFISH to design three sets of FISH probes. These allowed direct simultaneous detection of class switch recombination in both immunoglobulin-heavy chain alleles in single cells from a population of cultured primary B cells. It directly demonstrated asynchrony of the class switch recombination in the two alleles in structurally preserved nuclei while permitting parallel readout of protein expression by immunofluorescence staining. This novel technique offers the possibility of gaining unprecedented insight into the molecular mechanisms involved in class switch recombination.
PMID: 23272136 [PubMed – in process]
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FDA may switch asthma, diabetes, migraine drugs to over-counter status
Arizona Daily Star Food and Drug Administration officials said Wednesday they are considering waiving prescription requirements for certain drugs used to treat ailments like diabetes, asthma and migraine. Driving the move is a wave of computer technology, … |
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Switch to juice? Soft drinks associated with asthma and COPD in new study
Examiner.com Asthma and COPD are correlated with high soft-drink consumption, according to February 7th's press release detailing this new study of nearly 17000 Australians. Asthma and COPD are respiratory disorders that can cause a variety of symptoms in those … |
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Patients' inhaler switch hotly debated in court
New Zealand Doctor Online The Symbicort inhaler's ability to control, prevent and relieve asthma for some patients without the need for a separate reliever has been argued as meriting full funding by Pharmac. The rapid action of the Symbicort Turbuhaler makes a critical … Pharmac taken to court over asthma subsidy |
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Switch to Powder-Free Latex Gloves Cuts Health Workers' Allergy Risk
U.S. News & World Report … and Environmental Medicine, received funding from the US Centers for Disease Control and Prevention's National Institute for Occupational Safety and Health. The American Academy of Allergy, Asthma and Immunology has more about latex allergy. |
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