A smarter way to track your asthma symptoms

A smarter way to track your asthma symptomsA new, free-to-download app from non-profit Allergy & Asthma Network could help people better monitor and understand how asthma affects them or their children and provide potentially valuable insights for healthcare professionals. Called the Asthma Storylines app and available for the iPhone, Android and the desktop, it can be used for tracking everything from frequency of specific symptoms and emotional impact, to setting up reminders for taking medication or for medical appointments. The idea of the app is to create a comprehensive picture of how asthma manifests itself in an individual over time and potentially identify triggers as much as patterns.


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Aerobic exercise may help control asthma symptoms – PhillyVoice.com


PhillyVoice.com

Aerobic exercise may help control asthma symptoms
PhillyVoice.com
While it's not surprising that asthma patients may benefit from aerobic exercise, the findings offer new evidence that physical activity can help even in patients who are already controlling symptoms with medication, said lead author Dr. Celso Carvalho
Aerobic exercise helpful for asthmaBusiness Insider
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Aerobic Exercise May Curb Severity of Asthma Symptoms : News : University Herald – University Herald


University Herald

Aerobic Exercise May Curb Severity of Asthma Symptoms : News : University Herald
University Herald
"People with asthma are often worried about exercising as they fear it may trigger their symptoms; however this study gives us more evidence that exercise can actually be beneficial for people with asthma," Andrew Proctor, director of advice and

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Toluene diisocyanate: Induction of the autotaxin-lysophosphatidic acid axis and its association with airways symptoms.

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Toluene diisocyanate: Induction of the autotaxin-lysophosphatidic acid axis and its association with airways symptoms.

Toxicol Appl Pharmacol. 2015 Jun 11;

Authors: Broström JM, Ye ZW, Axmon A, Littorin M, Tinnerberg H, Lindh CH, Zheng H, Ghalali A, Stenius U, Jönsson BA, Högberg J

Abstract
Diisocyanates are industrial chemicals which have a wide range of applications in developed and developing countries. They are notorious lung toxicants and respiratory sensitizers. However, the mechanisms behind their adverse effects are not adequately characterized. Autotaxin (ATX) is an enzyme producing lysophosphatidic acid (LPA), and the ATX-LPA axis has been implicated in lung related inflammatory conditions and diseases, including allergic asthma, but not to toxicity of environmental low-molecular-weight chemicals. We investigated effects of TDI on ATX induction in human lung epithelial cell models, and we correlated LPA-levels in plasma to biomarkers of toluene diisocyanate (TDI) exposure in urine collected from workers exposed to<5p.p.b.(parts per billion). Information on workers’ symptoms was collected through interviews. One nM TDI robustly induced ATX release within 10min in vitro. A P2X7- and P2X4-dependent microvesicle formation was implicated in a rapid ATX release and a subsequent protein synthesis. Co-localization between purinergic receptors and ATX was documented by immunofluorescence and confocal microscopy. The release was modulated by monocyte chemoattractant protein-1 (MCP-1) and by extracellular ATP. In workers, we found a dose-response relationship between TDI exposure biomarkers in urine and LPA levels in plasma. Among symptomatic workers reporting “sneezing”, the LPA levels were higher than among non-symptomatic workers. This is a first report indicating induction of the ATX-LPA axis by an environmental low-molecular-weight chemical, and our data suggest a role for the ATX-LPA axis in TDI toxicity.

PMID: 26072274 [PubMed – as supplied by publisher]

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Aerobic Exercise Improved Some Asthma Symptoms – Medscape


Zee News

Aerobic Exercise Improved Some Asthma Symptoms
Medscape
Aerobic exercise, in the form of twice-a-week treadmill workouts, improved bronchial hyperresponsiveness in adults with moderate or severe persistent asthma, according to a small study published online June 10 in Thorax. "These results suggest that
Aerobic exercise may cut asthma severityZee News
Exercise May Alleviate Severe Asthma SymptomsUniversity Herald

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