Breathe Well Live Well
Condition: Patients With Asthma-COPD Overlap Syndrome (ACOS)
Intervention:
Sponsors: AstraZeneca; ASK CRE Private Limited
Not yet recruiting – verified August 2016
View full post on ClinicalTrials.gov: asthma | Studies received in the last 14 days
Condition: Hypereosinophilic Syndrome
Interventions: Drug: Mepolizumab 300 mg; Drug: Placebo matching mepolizumab; Drug: Active OCS capsules (5 mg prednisolone or prednisone); Drug: Placebo matching OCS capsules
Sponsor: GlaxoSmithKline
Not yet recruiting – verified July 2016
View full post on ClinicalTrials.gov: asthma | Studies received in the last 14 days
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The asthma–COPD overlap syndrome: do we really need another syndrome in the already complex matrix of airway …
Dove Medical Press Abstract: The term asthma–COPD overlap syndrome (ACOS) is one of multiple terms used to describe patients with characteristics of both COPD and asthma, representing ~20% of patients with obstructive airway diseases. The recognition of both sets of … |
View full post on asthma – Google News
Health24 |
ACOS – the little known syndrome asthma sufferers need to know about
Health24 The 3rd of May marks World Asthma Day – a global initiative aimed at improving asthma awareness and care across the globe. While most people know a bit about asthma, very few are aware of asthma-COPD overlap syndrome (ACOS) – a condition that … |
View full post on asthma – Google News
dailyRx News |
How is Asthma Linked to Polycystic Ovarian Syndrome?
dailyRx News Researchers from Australia found that women who have PCOS are also more likely to have asthma. Asthma is a chronic lung disease that causes inflammation and narrowing of the airways. The study also showed links between asthma, PCOS and excess … |
View full post on asthma – Google News
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Related Articles |
Epigenetic Dysfunction in Turner Syndrome Immune Cells.
Curr Allergy Asthma Rep. 2016 May;16(5):36
Authors: Thrasher BJ, Hong LK, Whitmire JK, Su MA
Abstract
Turner syndrome (TS) is a chromosomal condition associated with partial or complete absence of the X chromosome that involves characteristic findings in multiple organ systems. In addition to well-known clinical characteristics such as short stature and gonadal failure, TS is also associated with T cell immune alterations and chronic otitis media, suggestive of a possible immune deficiency. Recently, ubiquitously transcribed tetratricopeptide repeat on the X chromosome (UTX), a histone H3 lysine 27 (H3K27) demethylase, has been identified as a downregulated gene in TS immune cells. Importantly, UTX is an X-linked gene that escapes X-chromosome inactivation and thus is haploinsufficient in TS. Mice with T cell-specific UTX deficiency have impaired clearance of chronic viral infection due to decreased frequencies of T follicular helper (Tfh) cells, which are critical for B cell antibody generation. In parallel, TS patients have decreased Tfh frequencies in peripheral blood. Together, these findings suggest that haploinsufficiency of the X-linked UTX gene in TS T cells underlies an immune deficit, which may manifest as increased predisposition to chronic otitis media.
PMID: 27039394 [PubMed – in process]
View full post on pubmed: asthma
Tech Times |
New research links polycystic ovary syndrome, obesity to asthma in reproductive-age women
News-Medical.net Among reproductive-age women, polycystic ovary syndrome (PCOS) as well as overweight and obesity are independently linked with asthma, new preliminary research from Australia suggests. The results will be presented in a poster Saturday, April 2, … New Study Links Asthma To Polycystic Ovary Syndrome, Excess Weight Women With PCOS May Have Higher Asthma Rates PCOS, overweight, obesity increase risk for asthma |
View full post on asthma – Google News
Tech Times |
New Study Links Asthma To Polycystic Ovary Syndrome, Excess Weight
Tech Times Trying to find out the connection between asthma and women in childbearing ages, as well as the impact of excess weight in the chances of asthma risk among PCOS women, the researchers randomly chose 9,145 PCOS women between the ages of 28 and … Women With PCOS May Have Higher Asthma Rates Asthma is associated with polycystic ovary syndrome and excess weight PCOS, overweight, obesity increase risk for asthma |
View full post on asthma – Google News
NDTV |
Asthma is associated with polycystic ovary syndrome and excess weight
Science Codex Boston, MA–Among reproductive-age women, polycystic ovary syndrome (PCOS) as well as overweight and obesity are independently linked with asthma, new preliminary research from Australia suggests. The results will be presented in a poster Saturday, … Women With PCOS May Have Higher Asthma Rates PCOS, overweight, obesity increase risk for asthma Excess Weight Can Increase Odds Of Asthma In Women, Says Study |
View full post on asthma – Google News
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Asthma is associated with polycystic ovary syndrome and excess weight
Medical Xpress Among reproductive-age women, polycystic ovary syndrome (PCOS) as well as overweight and obesity are independently linked with asthma, new preliminary research from Australia suggests. The results will be presented in a poster Saturday, April 2, … |
View full post on asthma – Google News