Single Combined Asthma Inhaler Better Than Recommended Treatment – Medical News Today


Telegraph.co.uk

Single Combined Asthma Inhaler Better Than Recommended Treatment
Medical News Today
Using two asthma medications combined in a single inhaler provides superior rescue and preventive treatment than guideline-based treatments among adults whose asthma symptoms are not well controlled, according to two large, randomized clinical trials
Combo Inhaler May Give Better Relief for Some With AsthmaU.S. News & World Report
Single inhaler asthma therapy betterWebMD.Boots.com
Dual-purpose asthma inhalers more effectiveTelegraph.co.uk
Exchange Morning Post (press release)
all 5 news articles »

View full post on asthma – Google News

Hesperidin-3′-o-methylether is more potent than hesperidin in phosphodiesterase inhibition and suppression of ovalbumin-induced airway hyperresponsiveness.

Hesperidin-3′-o-methylether is more potent than hesperidin in phosphodiesterase inhibition and suppression of ovalbumin-induced airway hyperresponsiveness.

Evid Based Complement Alternat Med. 2012;2012:908562

Authors: Yang YL, Hsu HT, Wang KH, Wang CS, Chen CM, Ko WC

Abstract
Hesperidin is present in the traditional Chinese medicine, “Chen Pi,” and recently was reported to have anti-inflammatory effects. Therefore, we were interested in comparing the effects of hesperidin and hesperidin-3′-O-methylether on phosphodiesterase inhibition and airway hyperresponsiveness (AHR) in a murine model of asthma. In the present results, hesperidin-3′-O-methylether, but not hesperidin, at 30??mol/kg (p.o.) significantly attenuated the enhanced pause (P(enh)) value, suppressed the increases in numbers of total inflammatory cells, macrophages, lymphocytes, neutrophils, and eosinophils, suppressed total and OVA-specific immunoglobulin (Ig)E levels in the serum and BALF, and enhanced the level of total IgG(2a) in the serum of sensitized and challenged mice, suggesting that hesperidin-3′-O-methylether is more potent than hesperidin in suppression of AHR and immunoregulation. The different potency between them may be due to their aglycons, because these two flavanone glycosides should be hydrolyzed by ?-glucosidase after oral administration. Neither influenced xylazine/ketamine-induced anesthesia, suggesting that they may have few or no adverse effects, such as nausea, vomiting, and gastric hypersecretion. In conclusion, hesperidin-3′-O-methylether is more potent in phosphodiesterase inhibition and suppression of AHR and has higher therapeutic (PDE4(H)/PDE4(L)) ratio than hesperidin. Thus, hesperidin-3′-O-methylether may have more potential for use in treating allergic asthma and chronic obstructive pulmonary disease.

PMID: 23082087 [PubMed – in process]

View full post on pubmed: asthma

More than 75% of the Asthma Patient Care Costs Are Attributed to Severe … – Einnews Portugal

More than 75% of the Asthma Patient Care Costs Are Attributed to Severe
Einnews Portugal
Over 150 delegates from more than 30 countries are meeting in Gothenburg, Sweden,at the International Severe Asthma Forum, ISAF, 2012 organised by the European Academy of Allergy and Clinical Immunology, EAACI. ISAF 2012 aims to respond to the

and more »

View full post on asthma – Google News

More than 75% of the Asthma Patient Care Costs Are Attributed to … – Einnews Portugal

More than 75% of the Asthma Patient Care Costs Are Attributed to …
Einnews Portugal
More than 75% of the Asthma Patient Care Costs Are Attributed to … [12 Oct 2012] PR Newswire; Disney's Club Penguin Launches New Interactive Guide to Help Parents … [12 Oct 2012] PR Newswire; Swissvoice Will Present its Full Range of CAT-iq2.0

and more »

View full post on asthma – Google News

Inner City Infants Have Different Patterns of Viral Respiratory Illness Than … – Infection Control Today

Inner City Infants Have Different Patterns of Viral Respiratory Illness Than
Infection Control Today
Children living in low-income urban areas appear especially prone to developing asthma, possibly related to infections they acquire early in life. In a new study in the Journal of Infectious Diseases, researchers from the University of Wisconsin in

and more »

View full post on asthma – Google News

Inner city infants have different patterns of viral respiratory illness than … – Science Codex

Inner city infants have different patterns of viral respiratory illness than
Science Codex
Children living in low-income urban areas appear especially prone to developing asthma, possibly related to infections they acquire early in life. In a new study in The Journal of Infectious Diseases, available online, researchers from the University

and more »

View full post on asthma – Google News

Childhood asthma may be more closely linked to traffic fumes than previously … – GlobalPost


ScienceBlog.com (blog)

Childhood asthma may be more closely linked to traffic fumes than previously
GlobalPost
Fresh snow blankets the mountains behind the downtown skyline after a series of storms that hammered northern California delivered much needed precipitation to the Greater Los Angeles Area January 7, 2008 in Los Angeles, California. The American Lung
Near-roadway air pollution a major contributor to L,A. asthmaScienceBlog.com (blog)
Roads' impact on asthma underestimatedOnMedica
HEALTH: Freeway pollution risk 'very important,' researcher saysPress-Enterprise
Daily Mail –The Atlantic Cities
all 11 news articles »

View full post on asthma – Google News

Children who use steroids for asthma may be shorter than their peers as adults – Washington Post

Children who use steroids for asthma may be shorter than their peers as adults
Washington Post
Children with chronic asthma. Corticosteroid medications, which suppress inflammation, are a standard treatment for asthma because they help control symptoms and improve lung function. More than 25 million people in the United States have asthma, and

View full post on asthma – Google News