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People voice their concerns to KISD over asthma incident
The Killeen Daily Herald Gateway Middle School student Anthony Ruelas, 15, was suspended two weeks ago after disobeying orders to stay seated during math class when a fellow classmate was visibly in distress, purportedly suffering from an asthma attack. Ruelas' mother, Mandy … |
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Nature World Report |
(+Video) Asthma treatment in babies under two stunts their growth
Nature World Report Researchers from Kuopio University Hospital and University of Eastern Finland analysed information on the height, weight and asthma medicine intake of 12,482 Finnish children aged 0-24 months. They found that children who used inhaled corticosteroids … Asthma steroids 'could stunt growth' Asthma medication for infants could lead to growth issues: Finnish Research Is your child taking asthma steroids? Researchers says Asthma medications … |
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Nature World Report |
Asthma treatment in babies can affect their growth
Nature World Report Researchers from Kuopio University Hospital and University of Eastern Finland analysed information on the height, weight and asthma medicine intake of 12,482 Finnish children aged 0-24 months. They found that children who used inhaled corticosteroids … Asthma steroids 'could stunt growth' Asthma medication stunts growth among infants: Finnish Research Is your child taking asthma steroids? Researchers says Asthma medications … |
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Parents serve as coaches for asthma patients and their families
WAAY One in 10 children are living with asthma right now. It's a life-long condition and costs $18 billion a year in medical expenses, lost work and school days. Now, there's a new approach to help your children's health while saving time and money. Quin … |
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Daily Mail |
Forget inhalers… asthma sufferers in India gulp down LIVE FISH to ease their …
Daily Mail But rather than a puff from an inhaler or a pill – the boy is forced to swallow a live fish. Every year, thousands of Indians line up to swallow the slimy sea creatures, a traditional treatment for the condition. Asthma sufferers gather every June in … |
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Nutrition and dietary intake and their association with mortality and hospitalisation in adults with chronic kidney disease treated with haemodialysis: protocol for DIET-HD, a prospective multinational cohort study.
BMJ Open. 2015;5(3):e006897
Authors: Palmer SC, Ruospo M, Campbell KL, Garcia Larsen V, Saglimbene V, Natale P, Gargano L, Craig JC, Johnson DW, Tonelli M, Knight J, Bednarek-Skublewska A, Celia E, Del Castillo D, Dulawa J, Ecder T, Fabricius E, Frazão JM, Gelfman R, Hoischen SH, Schön S, Stroumza P, Timofte D, Török M, Hegbrant J, Wollheim C, Frantzen L, Strippoli GF, DIET-HD Study investigators
Abstract
INTRODUCTION: Adults with end-stage kidney disease (ESKD) treated with haemodialysis experience mortality of between 15% and 20% each year. Effective interventions that improve health outcomes for long-term dialysis patients remain unproven. Novel and testable determinants of health in dialysis are needed. Nutrition and dietary patterns are potential factors influencing health in other health settings that warrant exploration in multinational studies in men and women treated with dialysis. We report the protocol of the “DIETary intake, death and hospitalisation in adults with end-stage kidney disease treated with HaemoDialysis (DIET-HD) study,” a multinational prospective cohort study. DIET-HD will describe associations of nutrition and dietary patterns with major health outcomes for adults treated with dialysis in several countries.
METHODS AND ANALYSIS: DIET-HD will recruit approximately 10?000 adults who have ESKD treated by clinics administered by a single dialysis provider in Argentina, France, Germany, Hungary, Italy, Poland, Portugal, Romania, Spain, Sweden and Turkey. Recruitment will take place between March 2014 and June 2015. The study has currently recruited 8000 participants who have completed baseline data. Nutritional intake and dietary patterns will be measured using the Global Allergy and Asthma European Network (GA(2)LEN) food frequency questionnaire. The primary dietary exposures will be n-3 and n-6 polyunsaturated fatty acid consumption. The primary outcome will be cardiovascular mortality and secondary outcomes will be all-cause mortality, infection-related mortality and hospitalisation.
ETHICS AND DISSEMINATION: The study is approved by the relevant Ethics Committees in participating countries. All participants will provide written informed consent and be free to withdraw their data at any time. The findings of the study will be disseminated through peer-reviewed journals, conference presentations and to participants via regular newsletters. We expect that the DIET-HD study will inform large pragmatic trials of nutrition or dietary interventions in the setting of advanced kidney disease.
PMID: 25795691 [PubMed – as supplied by publisher]
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The Inquisitr |
Breastfeeding Babies Influences Their Immune System And Susceptibility To …
Tech Times Mothers who breastfeed babies in the first month are helping influence the nature of bacteria in the infant's digestive system, which in turn boosts the immune system to provide protection against conditions like allergies or asthma, researchers say … Breastfeeding Puts Children At Lower Risk For Allergies And Asthma, Says New … Breastfeeding Benefits Babies' Immune Systems Within First Month; Provides … Research links infants' microbiome to development of immune system, allergic … |
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Undifferentiated Bronchial Fibroblasts Derived from Asthmatic Patients Display Higher Elastic Modulus than Their Non-Asthmatic Counterparts.
PLoS One. 2015;10(2):e0116840
Authors: Sarna M, Wojcik KA, Hermanowicz P, Wnuk D, Burda K, Sanak M, Czy? J, Michalik M
Abstract
During asthma development, differentiation of epithelial cells and fibroblasts towards the contractile phenotype is associated with bronchial wall remodeling and airway constriction. Pathological fibroblast-to-myofibroblast transition (FMT) can be triggered by local inflammation of bronchial walls. Recently, we have demonstrated that human bronchial fibroblasts (HBFs) derived from asthmatic patients display some inherent features which facilitate their FMT in vitro. In spite of intensive research efforts, these properties remain unknown. Importantly, the role of undifferentiated HBFs in the asthmatic process was systematically omitted. Specifically, biomechanical properties of undifferentiated HBFs have not been considered in either FMT or airway remodeling in vivo. Here, we combine atomic force spectroscopy with fluorescence microscopy to compare mechanical properties and actin cytoskeleton architecture of HBFs derived from asthmatic patients and non-asthmatic donors. Our results demonstrate that asthmatic HBFs form thick and aligned ‘ventral’ stress fibers accompanied by enlarged focal adhesions. The differences in cytoskeleton architecture between asthmatic and non-asthmatic cells correlate with higher elastic modulus of asthmatic HBFs and their increased predilection to TGF-?-induced FMT. Due to the obvious links between cytoskeleton architecture and mechanical equilibrium, our observations indicate that HBFs derived from asthmatic bronchi can develop considerably higher static tension than non-asthmatic HBFs. This previously unexplored property of asthmatic HBFs may be potentially important for their myofibroblastic differentiation and bronchial wall remodeling during asthma development.
PMID: 25679502 [PubMed – as supplied by publisher]
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Lung Disease News |
Study Shows People with Asthma Avoid Talking With Their Doctors About Work …
Lung Disease News shutterstock_247085752 According to a recent study, people with asthma avoid talking with their doctors about work-related asthma. The findings were published in the current issue of Annals of Allergy, Asthma and Immunology. The study reveals that … |
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Study shows that babies born prematurely grow out of their asthma
News-Medical.net Large-scale Danish study from the University of Copenhagen shows that premature babies grow out of the asthma which they are likely to develop in early life. Babies born prematurely are more likely to develop asthma, but they grow out of it. This is … |
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