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Asthma treatment passes trial
Investor’s Business Daily Regeneron Pharmaceuticals (NASDAQ:REGN) and Sanofi (NYSE:SNY) jointly announced positive results from a phase 2 study of dupilumab in patients with moderate to severe uncontrolled asthma, who often struggle with daily symptoms and recurring … |
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World First Travel Insurance |
Asthma vs. COPD, similar symptoms—different causes and treatment
Medical Xpress Coughing, wheezing and shortness of breath are symptoms asthma sufferers are used to. They are also the symptoms of chronic obstructive pulmonary disease (COPD). For sufferers, as well as physicians, it can be difficult to tell the difference between … Mouse Infestations Cause More Asthma Symptoms than Cockroach Exposure New drug hope for asthma sufferers Allergic to Penicillin? Maybe Not |
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Asthma vs. COPD, similar symptoms — Different causes and treatment
EurekAlert (press release) ATLANTA, GA (November 7, 2014) – Coughing, wheezing and shortness of breath are symptoms asthma sufferers are used to. They are also the symptoms of chronic obstructive pulmonary disease (COPD). For sufferers, as well as physicians, it can be difficult … Mouse Infestations Cause More Asthma Symptoms than Cockroach Exposure |
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Medical News Today |
Asthma vs. COPD, Similar Symptoms – Different Causes and Treatment
Newswise (press release) Newswise — ATLANTA, GA (November 7, 2014) – Coughing, wheezing and shortness of breath are symptoms asthma sufferers are used to. They are also the symptoms of chronic obstructive pulmonary disease (COPD). For sufferers, as well as physicians, … How does stigma surrounding COPD affect research and care? |
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Asthma Indication Sought for COPD Treatment
Pharmacy Times “There is a critical need for a new treatment option to provide benefits to, and improve outcomes for, patients with asthma,” said Klaus Dugi, chief medical officer for Boehringer Ingelheim, in a press release. “The FDA's acceptance of our application … |
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| Related Articles |
Treatment of Aspirin Exacerbated Respiratory Disease with a Low Salicylate Diet: A Pilot Crossover Study.
Otolaryngol Head Neck Surg. 2014 Oct 24;
Authors: Sommer DD, Hoffbauer S, Au M, Sowerby LJ, Gupta MK, Nayan S
Abstract
OBJECTIVE: Aspirin exacerbated respiratory disease (AERD) is comprised of aspirin/acetylsalicylic acid (ASA) sensitivity, bronchial asthma, and nasal polyposis. Treatment of this condition is challenging and may include topical/systemic steroids, endoscopic sinus surgery, and/or aspirin desensitization.
STUDY DESIGN: A prospective crossover pilot study (n = 10) was conducted in which patients were randomized into either of 2 groups with 6 weeks of regular diet (R) or 6 weeks of a low salicylate diet (LS).
SETTING: The study was conducted in a tertiary otolaryngology clinic.
SUBJECTS: Patients with AERD were enrolled in the study.
METHODS: Subjective (Sino-nasal Outcome Test-22 [SNOT-22], Nasal Sinus Symptom Scale [NSSS], and the Asthma Control Questionnaire-7 [ACQ-7]) and objective outcome instruments (Peri-Operative Sinus Evaluation [POSE] and Lund-Kennedy Endoscopic Score [LKES]) were used to evaluate patients at baseline, 6 weeks (at crossover), and 12 weeks.
RESULTS: Wilcoxon rank sum tests demonstrated that patients on the low salicylate diet had improved scores compared to their regular diet when evaluated by 4 of the 5 outcome measures (SNOT-22 pLS = 0.0059, NSSS pLS = 0.0195, LKES pLS = 0.0039, POSE pLS = 0.005).
CONCLUSION: Results of the pilot study indicate that implementation of a low salicylate diet improves the nasal symptoms and nasal endoscopy findings of individuals with AERD. Further research is required to support these findings.
PMID: 25344589 [PubMed – as supplied by publisher]
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HCPLive |
Researchers Pinpoint Novel Asthma Treatment Target
HCPLive Existing medication containing inhaled steroids, are highly effective at controlling regular asthma symptoms, but during an attack the symptoms worsen and can lead to the patient going to hospital,” commented Sebastian Johnston of the National Heart … |
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Research and Markets: Roche/Genentech/Novartis' Asthma Treatment – Xolair …
Business Wire (press release) Roche/Genentech/Novartis' Xolair (omalizumab) is currently the only FDA-approved biologic used in the treatment of asthma. This drug is a recombinant humanized mAb that binds and neutralizes IgE with the same high affinity as its cognate receptor, FceRI. Research and Markets: Merck's Dulera Asthma Treatment – Forecast and Market … |
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Washington University Record |
Treatment study seeks African-Americans with asthma
Washington University Record Doctors at Washington University School of Medicine in St. Louis are seeking African-Americans with asthma to participate in a new study evaluating treatment for this common breathing disorder. The study is the first to focus exclusively on African … |
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UWM researchers land NIH grant to develop asthma treatment
Milwaukee Journal Sentinel (blog) The National Institutes of Health awarded a grant worth almost $2 million to chemists at the University of Wisconsin-Milwaukee who are working to find a new drug for asthma. The four-year grant is for research to develop an asthma drug with fewer side … |
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