GlaxoSmithKline’s asthma med among top-selling drugs in U.S. – Triangle Business Journal (blog)

GlaxoSmithKline's asthma med among top-selling drugs in U.S.
Triangle Business Journal (blog)
The British drug company, which has its North American headquarters in Research Triangle Park, comes in fifth with asthma medicine Advair Diskus. The rest of the top five: Otsuka Pharmaceuticals' Abilify. AstraZeneca Pharmaceuticals' (NYSE: AZN) Nexium

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Nearly 26 Million Americans Continue to Live with Asthma, EPA says

Nearly 26 Million Americans Continue to Live with Asthma, EPA says / SC, IN, TX programs honored as national models for asthma care

Throughout May, as part of Asthma Awareness Month, EPA is encouraging Americans to take simple steps to prevent asthma attacks while also honoring three leading asthma management programs for their efforts to improve the lives of people with asthma in underserved communities.

The economic costs of asthma amounts to more than $56 billion per year from direct medical costs and indirect costs, such as missed school and work days. During President Obama’s administration, EPA has made significant progress in improving air quality. In 2012, EPA strengthened the national standard for fine particle pollution, often called soot, which has been linked to a wide range of serious health effects including aggravated asthma. In 2011, former EPA Administrator Lisa P. Jackson signed the Mercury and Air Toxics Standards (MATS), which will help avoid 130,000 cases of aggravated asthma by 2016.

“Today one out of every 12 people suffers from asthma – and the numbers are increasing year after year,” said EPA Acting Administrator Bob Perciasepe. “With President Obama’s support, EPA has taken commonsense steps towards cleaner air, which translates to fewer asthma attacks and instances of other respiratory diseases. As we mark Asthma Awareness Month, we call on all Americans to learn more about the easy ways they can avoid asthma triggers and prevent future attacks from happening to them or their loved ones.”

Asthma is a national epidemic, affecting nearly 26 million people, including seven million children and disproportionally affecting low income and minority communities. The EPA is conducting a coordinated approach to promoting scientific understanding of environmental asthma triggers and ways to manage asthma through research, education and community-focused outreach.

Serving as a national model for asthma care, the following programs are leading the way in addressing asthma disparities and are the winners of the 2013 National Environmental Leadership Award in Asthma Management:

· Greenville Health System (Greenville, S.C.): A multidisciplinary, multilingual, family-centered program that is able to, with partner collaboration, provide medical care, case management, school/daycare visits, and environmental control home visits for over 4,000 children and adolescents with asthma, especially those who have limited access to health care.
· Parkview Health (Fort Wayne, Ind.): The program addresses the growing incidence of asthma-related illnesses in the communities they serve. Support services, resources and age-appropriate educational information on asthma are provided. Those that are a part of the Emergency Department Asthma Call Back Program, including a high number of low-income individuals, are provided home visits to assess and minimize environmental asthma triggers.
· North East Independent School District (San Antonio, Texas): The urban, diversified school district’s Asthma Awareness Education Program targets the more than 8,000 students with asthma and provides direct case management strategies including counseling with families, home visits, coordination with asthma specialists, and asthma education.

State and local asthma programs across the country can take action throughout the month of May by holding community-based events to increase awareness of asthma triggers and the successful strategies for managing exposure to triggers.

American’s who suffer from asthma can learn to control their symptoms and still maintain active lifestyles with these three simple steps:

1. Identify asthma triggers and avoid them. Air pollution, dust mites, secondhand smoke, mold, pests, pet dander can trigger asthma attacks. Identify and avoid personal asthma triggers – different people are affected differently. Work with your doctor to identify and avoid your triggers.
2. Create an asthma action plan. An asthma action plan will enable you to monitor your asthma on a daily basis and communicate important information about your personal asthma triggers and asthma control strategies. Ask your doctor to assist you in creating an asthma action plan.
3. Pay attention to air quality. Exposure to ozone and particle pollution can cause asthma attacks. When air quality is low, people with asthma may want to stay indoors, use air conditioning instead of open windows, and avoid outdoor activity. Check local air quality conditions and download an Air Quality Index app for smart phones.

Are You Allergic to the United States? – U.S. News & World Report


U.S. News & World Report

Are You Allergic to the United States?
U.S. News & World Report
That protection doesn't last forever, however: People who have been in the United States for at least a decade lose that protection and are more likely to develop asthma, hay fever and eczema, according to the study, published in the Journal of the
US-born kids have more allergies, asthmaReuters
Being Born in the U.S. Increases Children's Risk of Allergic DiseasesCounsel & Heal
Kids born outside the US have lower allergy riskConsumerAffairs
Science Codex –Raw Story –Yahoo! News
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Insurance Loss Hampers Young People With Asthma – U.S. News & World Report


Parent Herald

Insurance Loss Hampers Young People With Asthma
U.S. News & World Report
"This study suggests that expanding insurance coverage will help many young adults with asthma receive the care they need," study leader Kao-Ping Chua, a staff physician in the division of emergency medicine at Boston Children's Hospital, said in a
Expanded Insurance Coverage May Help Youngsters Suffering from Asthma Parent Herald

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Oral Allergy Treatment May Ease Asthma Study Finds

Oral Allergy Drops are a Pretty Good Option for Some Allergy and Allergic Asthma Sufferers, Study Review Shows

A scientific review of 63 published studies affirms that putting small amounts of purified grasses, ragweed, dust mites, pollen and mold, in liquid drops under the tongue is a safe and effective alternative to weekly injections of those allergens or the use of other medications, in treating symptoms of allergies and allergic asthma in some people.

Results of the review, conducted by researchers at Johns Hopkins, are contained in a report to be published in the Journal of the American Medical Association online March 27. The report is believed to be the largest synopsis of its kind, reviewing previous research comparing various therapies designed to stop the wheezing, sneezing and runny nose that accompany allergic rhinoconjunctivitis and allergic asthma, researchers say.

Specifically, the Johns Hopkins team analyzed 63 studies, involving some 5,131 participants, almost all in Europe, where allergy drops, or so-called sublingual immunotherapy, have been widely available for nearly two decades. Sublingual therapies have not been approved for use by the U.S. Food and Drug Administration, but physicians in the United States do use the drops “off-label” for some patients.

In eight of 13 studies evaluated, researchers found what they say is “strong evidence” that drop therapy produced a 40 percent or greater reduction in coughing, wheezing, and tightness in the chest compared with other treatments, including inhaled steroids.

In nine of 36 studies comparing allergy drops to other allergy treatments, including antihistamines and nasal steroid sprays, researchers found that allergy drops produced a 40 percent or greater reduction in symptoms of runny nose, sneezing and nasal congestion, results which they describe as “moderate evidence” in support of using sublingual immunotherapy.

“Our findings are clear evidence that sublingual immunotherapy in the form of allergy drops are an effective potential treatment option for millions of Americans suffering from allergic asthma and allergic rhinoconjunctivitis,” says senior study investigator Sandra Lin, M.D.

According to Lin, an associate professor of otolaryngology-head and neck surgery at the Johns Hopkins University School of Medicine, allergy drops are more convenient for many people because they can be taken at home, and allow such individuals to avoid the discomfort and travel time needed for regularly scheduled trips to the physician’s office for an allergy shot. Lin says that, according to current estimates, as many as 40 percent of Americans suffer from some form of allergic rhinitis or allergic asthma.

Lin cautions that drop therapies may not be for all sufferers of allergic rhinoconjunctivitis and allergic asthma, but that many will want to weigh the risks and benefits of sublingual immunotherapy before deciding on long-term treatment options.

Study funding was provided by the U.S. Agency for Healthcare Research and Quality. The corresponding grant number is HHSA 290-2007-10061.

Other Johns Hopkins researchers involved include Jodi Segal, M.D., M.P.H.; Darcy Ward, B.A.; Yohalakshmi Chelladurai, M.B.B.S.; Catalina Suarez-Cuervo, M.D.; Murugappan Ramanathan, M.D.; Julia Kim, M.D., M.P.H.; and Nkiruka Erekosima, M.D., M.P.H.

Combo Inhaler May Give Better Relief for Some With Asthma – U.S. News & World Report

Combo Inhaler May Give Better Relief for Some With Asthma
U.S. News & World Report
"The SMART regime was more effective as a treatment for asthma than the conventional treatment, where you just use a inhaler at a fixed maintenance dose and a short-acting inhaler for the relief of symptoms," said Dr. Richard Beasley, director of the
Single inhaler asthma therapy better at preventing attacks than recommended Exchange Morning Post (press release)

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