Very poorly controlled asthma lasts more than a decade for half of patients – The Pharmaceutical Journal


The Pharmaceutical Journal

Very poorly controlled asthma lasts more than a decade for half of patients
The Pharmaceutical Journal
The researchers, who presented their results at the American Thoracic Society International Conference on 15–18 May 2016, say that alternative treatment strategies and helping patients to quit smoking could improve the asthma control of these patients.

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Very poorly controlled asthma may persist for more than a decade despite treatment – Healio

Very poorly controlled asthma may persist for more than a decade despite treatment
Healio
Almost half of patients with severe or difficult-to-treat asthma in the TENOR II cohort still had symptoms of very poorly controlled asthma following more than a decade of treatment, according to data presented at the annual American Thoracic Society …

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Very poorly controlled asthma highly prevalent in TENOR II cohort after more than a decade – EurekAlert (press release)

Very poorly controlled asthma highly prevalent in TENOR II cohort after more than a decade
EurekAlert (press release)
ATS 2016, SAN FRANCISCO — Nearly half (48%) of patients with severe or difficult-to-treat asthma in The Epidemiology and Natural History of Asthma: Outcomes and Treatment Regimens follow-up study (TENOR II) still had very poorly controlled (VPC) …

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[Very preterm births in French Polynesia: Update and proposal for follow-up.]

[Very preterm births in French Polynesia: Update and proposal for follow-up.]

Arch Pediatr. 2014 Dec 29;

Authors: Besnard M, Kuo P, Pawlotsky F, Guyot D, Elie V, Papouin-Rauzy M

Abstract
INTRODUCTION: The care of premature infants in French Polynesia is complicated by this country’s geographic isolation. We undertook an evaluation of the medical care of very premature infants (VPIs) to find local solutions to this problem.
OBJECTIVES: The objectives were to determine the incidence, mortality, and the short- and long-term outcome of very preterm infants in French Polynesia.
METHODS: We retrospectively reviewed the medical charts of all infants born alive at<32 gestational age (GA) and>24 GA from January 2007 to December 2011. Perinatal characteristics and outcomes were examined by univariate and multivariate analysis.
RESULTS: In total, 204 VPIs were born during the 5-year study period, comprising 0.9% of all births. Infants less than 28 GA comprised 0.1% of all births. Sixty-two percent of mothers were of extreme age including 43% less than 25 years old. Prematurity was attributed to spontaneous preterm labor in 63% of cases and preeclampsia in 29%. Spontaneous multiple pregnancies comprised 15% of the cases. Alcohol and tobacco consumption were frequently noted (>8% and 26% mothers, respectively). Seventy-eight percent of VPIs had received prenatal steroids. Intrauterine growth was normal in 89%. Mortality occurred in 9.3% (19 patients). Mortality was higher with lower gestational age (P<0.05) and absence of prenatal steroids (P<0.05) in univariate and multivariate analysis. The primary cause of death was sepsis. Hyaline membrane disease occurred in 44% of patients, 80% of whom received surfactant therapy. In total, 16.2% newborns developed bronchodysplasia, 3.4% necrotizing enterocolitis, 3% cerebral hemorrhage, and 1.5% leukomalacia. Long-term outcome was marked by 52% of the patients lost to follow-up by 2 years of age, mostly because of geographic isolation. For the 72 patients followed-up, four developed asthma and three cerebral palsy; 70% were attending school by 3 years of age.
CONCLUSIONS: The incidence, mortality, and morbidity of very preterm birth in French Polynesia are comparable to reports from metropolitan centers in France. Conversely, nearly one-half of the patients were lost to follow-up, precluding meaningful information on intellectual development and other outcomes. We recommend organizing a long-term follow-up network to detect cognitive sequelae and adapting such a system to the geographical residence of French Polynesian families.

PMID: 25554672 [PubMed – as supplied by publisher]

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Study: Very few use EpiPen, asthma inhalers correctly – The Seattle Times

Study: Very few use EpiPen, asthma inhalers correctly
The Seattle Times
“We were pretty surprised,” said Dr. Rana Bonds, the allergist who led the research published Wednesday in the Annals of Allergy, Asthma and Immunology. “We send patients out with these devices that can save their lives and they don't know how to use …
Study shows epinephrine auto-injectors and asthma inhalers used incorrectlyMedical Xpress
Correct Use of Asthma, Allergy Devices Could Save LivesdailyRx
Moms of food-allergic kids need dietician's supportEurekAlert (press release)

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Asthma’s treatment pipeline very strong as more personalized medicines emerge – The Pharma Letter

Asthma's treatment pipeline very strong as more personalized medicines emerge
The Pharma Letter
According to research and consulting firm GlobalData's latest report, the most significant challenge in asthma therapeutics is posed by patients with severe forms of the disease, who remain uncontrolled and have frequent exacerbations, even with the …

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Indoor Mold Can Be Very Dangerous For Asthma Sufferers – RedOrbit


RedOrbit

Indoor Mold Can Be Very Dangerous For Asthma Sufferers
RedOrbit
Just to be clear, the Asthma and Allergy Foundation of America identifies that mold is a fungi which reproduces and grows through spreading spores in the wind outdoors and through air circulating indoors. In some individuals, these spores may cause
Indoor Mold May Pose a Significant Threat to Asthma SufferersUniversity Herald
Indoor Mold Exposure Can Post Health Risk To Asthma PatientsMedical Research News and Interviews_ MedicalResearch.com

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How Asthma sufferers can stay safe despite “very high” levels of air pollution … – ITV News


ITV News

How Asthma sufferers can stay safe despite "very high" levels of air pollution
ITV News
"The two thirds of people with asthma who find that air pollution makes their asthma worse will be at an increased risk of an attack following the alarming Defra warning of high pollution levels around the country. Asthma UK warns the 3.6 million
Asthma specialists fear wave of attacks from Saharan dust stormTelegraph.co.uk
UK smog alert: vulnerable people advised to stay indoorsThe Guardian
Warning to cut outdoor activityexpressandstar.com

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