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Childhood asthma linked to young adult COPD risk
Clinical Advisor HealthDay News — Children with persistent asthma and reduced growth of lung function may be at increased risk for chronic obstructive pulmonary disease (COPD) in early adulthood, according to a study published in the May 12 issue of the New England … Allergy Partners Announces Topic of the Month: COPD vs. Asthma |
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Respiratory hospital admissions in young children living near metal smelters, pulp mills and oil refineries in two Canadian provinces.
Environ Int. 2016 May 17;94:24-32
Authors: Brand A, McLean KE, Henderson SB, Fournier M, Liu L, Kosatsky T, Smargiassi A
Abstract
BACKGROUND: Industrial plants emit air pollutants like fine particles (PM2.5), sulfur dioxide (SO2) and nitrogen dioxide (NO2) that may affect the health of individuals living nearby.
OBJECTIVE: To assess the effects of community exposure to air emissions of PM2.5, SO2, and NO2 from pulp mills, oil refineries, metal smelters, on respiratory hospital admissions in young children in Quebec (QC) and British Columbia (BC), Canada.
METHODS: We assessed QC, BC and pooled associations between the following estimates of exposure and hospital admissions for asthma and bronchiolitis in children aged 2-4years for the years 2002-2010: i) Crude emission exposures at the residential postal codes of children, calculated by multiplying estimated daily emissions of PM2.5, SO2, or NO2 from all nearby (<7.5km) pulp mills, oil refineries, metal smelters emitting yearly ?50t and their total emissions, by the percent of the day each postal code was downwind; ii) Daily levels of these pollutants at central ambient monitoring stations nearby the industries and the children’s residences.
RESULTS: Seventy-one major industries were selected between QC and BC, with a total of 2868 cases included in our analyses. More cases were exposed to emissions from major industries in QC than in BC (e.g. 2505 admissions near SO2 industrial emitters in QC vs 334 in BC), although air pollutant levels were similar. Odds ratios (ORs) for crude refinery and smelter emissions were positive in QC but more variable in BC. For example with PM2.5 in QC, ORs were 1.13 per 0.15t/day (95% CI: 1.00-1.27) and 1.03 (95% CI: 0.99-1.07) for refinery and smelter emissions, respectively. Pooled results of QC and BC for crude total SO2 emissions from all sources indicated a 1% increase (0-3%) in odds of hospital admissions per 1.50t/day increase in exposure. Associations with measured pollutant levels were only seen in BC, with SO2 and NO2.
CONCLUSION: Hospital admissions for wheezing diseases in young children were associated with community exposure to industrial air pollutant emissions. Future work is needed to better assess the risk of exposure to complex mixture of air pollutants from multiple industrial sources.
PMID: 27203781 [PubMed – as supplied by publisher]
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Lack of asthma testing could risk the careers of young footballers
HealthCanal.com (press release) (blog) Teenagers who play in elite youth football leagues could be jeopardising their health and sporting potential because they aren't getting tested for asthma early in their career, suggests Brunel University London exercise and respiratory physiologist, … |
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Conditions: Individuality; Healthy; Asthma; Immune System and Related Disorders
Intervention: Biological: Pneumococcal Vaccination
Sponsor: Michigan State University
Recruiting – verified January 2016
View full post on ClinicalTrials.gov: asthma | received in the last 14 days
Zee News |
Asthma increases the risk of suffering from nearsightedness at young age
TheHealthSite People with asthma, sleep apnea or Down syndrome, have much higher odds of developing an eye condition that causes serious progressive nearsightedness at a relatively young age, new research has revealed. The researchers also confirmed that men … Asthma, sleep apnea may up risk of progressive eye condition |
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UCLA, USC partner on mHealth projects to help young asthma patients
FierceMobileHealthcare (press release) Scientists from University of California, Los Angeles, and the University of Southern California are embarking on a $6 million research effort to use smartphones and smartwatches to help young asthma sufferers improve thier health, according to an … App for Kids to ID Asthma Attack Triggers |
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Association between Dietary Patterns and Atopic Dermatitis in Relation to GSTM1 and GSTT1 Polymorphisms in Young Children.
Nutrients. 2015;7(11):9440-9452
Authors: Chung J, Kwon SO, Ahn H, Hwang H, Hong SJ, Oh SY
Abstract
Previous research suggests the association of glutathione S-transferase (GST) gene polymorphisms or diet, but no interactions between these factors in atopic dermatitis (AD). We conducted a community-based case-control study including 194 AD and 244 matched non-AD preschoolers. Glutathione S-transferase M1 (GSTM1) and T1 (GSTT1) present/null genotypes were evaluated uisng a multiplex PCR method. We measured dietary intakes by a validated food frequency questionnaire and constructed three dietary patterns such as “traditional healthy”, “animal foods”, and “sweets” diets. In stratified analyses by GST genotypes, the “traditional healthy” diet and reduced AD showed association only in the GSTM1-present group (odd ratio (OR) 0.31, 95% confidence interval (CI) 0.13-0.75). A similar pattern of the association existed in the combined GSTM1/T1 genotype that indicated the inverse association between the “traditional healthy” diet and AD in the double GSTM1/T1-present genotype group (OR 0.24, 95% CI 0.06-0.93). Results from the multiplicative test analyses showed that the “traditional healthy” diet on reduced AD was significant or borderline significant in the GSTM1-present group (OR 0.71, 95% CI 0.54-0.92 vs. GSTM1-null group) or the GSTM1/T1 double present group (OR 0.63, 95% CI 0.39-1.03 vs. GSTM1/T1 double null group). These findings demonstrate that the present type of GSTM1 may increase susceptibility to the potential effect of the “traditional healthy” diet on AD.
PMID: 26580648 [PubMed – as supplied by publisher]
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High levels of physical activity may worsen asthma control in young females
EurekAlert (press release) Among 526 adolescents and young adults who were asked about their exercise habits, those with asthma tended to report more physical activity than those without asthma. Compared with moderate physical activity, high physical activity levels were linked … |
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Asthma risk reduced in young children with pet dogs, says study
Caribbean360.com (subscription) “Earlier studies have shown that growing up on a farm reduces a child's risk of asthma to about half. We wanted to see if this relationship also was true for children growing up with dogs in their homes,” study author Dr Tove Fall said in a statement … |
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This Common Asthma Drug Made Old Rats Act Like Young Rats Again
Motherboard The latest stride toward immortality was unveiled last week at the Society for Neuroscience conference in Chicago, where a team of researchers presented findings that demonstrated how a common asthma medication can be repurposed to encourage … Alzheimer's breakthrough? Hay fever drug rejuvenates the brain and REVERSES … Wonder drug could slow and even STOP ageing |
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