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Allergic asthma: Researchers identify a key molecule
Medical Xpress In addition to hay fever, allergic asthma is currently considered to be one of the most widespread allergies. UFZ researchers and their colleagues from the University of Leipzig have recently been successful in finding a protein that plays a critical … |
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Dietary factors linked to asthma symptoms, allergic sensitization
Healio Having a canteen lunch one or two times per week was associated with wheeze development during the previous year (adjusted OR = 0.71; 95% CI, 0.52-0.96), lifetime asthma risk (adjusted OR = 0.76; 95% CI, 0.6-0.96) and sensitivity to allergies (adjusted … |
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Condition: Hay Fever
Interventions: Biological: Placebo solution; Biological: gpASIT+TM
Sponsor: BioTech Tools S.A.
Not yet recruiting – verified September 2015
View full post on ClinicalTrials.gov: asthma | received in the last 14 days
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Allergy immunotherapy prevents asthma in patients with allergic rhinitis
Healio “Allergy immunotherapy effectively prevents the progression of allergic rhinitis to asthma in a real-life setting. This asthma-preventive effect is strongest in products containing native allergens,” Jochen Schmitt, MD, MPH, of the Center for Evidence … |
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Related Articles |
Genetics of allergy and allergic sensitization: common variants, rare mutations.
Curr Opin Immunol. 2015 Sep 16;36:115-126
Authors: Bønnelykke K, Sparks R, Waage J, Milner JD
Abstract
Our understanding of the specific genetic lesions in allergy has improved in recent years due to identification of common risk variants from genome-wide association studies (GWAS) and studies of rare, monogenic diseases. Large-scale GWAS have identified novel susceptibility loci and provided information about shared genetics between allergy, related phenotypes and autoimmunity. Studies of monogenic diseases have elucidated critical cellular pathways and protein functions responsible for allergy. These complementary approaches imply genetic mechanisms involved in Th2 immunity, T-cell differentiation, TGF? signaling, regulatory T-cell function and skin/mucosal function as well as yet unknown mechanisms associated with newly identified genes. Future studies, in combination with data on gene expression and epigenetics, are expected to increase our understanding of the pathogenesis of allergy.
PMID: 26386198 [PubMed – as supplied by publisher]
View full post on pubmed: asthma
Condition: Allergic Rhinitis
Interventions: Drug: Levocetirizine; Drug: Desloratadine
Sponsor: Iuliu Hatieganu University of Medicine and Pharmacy
Completed – verified July 2015
View full post on ClinicalTrials.gov: asthma | received in the last 14 days
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Study Tests Effectiveness of Omalizumab in Treating Perennial Severe Allergic …
Lung Disease News Asthma is a common chronic condition of the airways that is complex and characterized by variable and regular symptoms, airflow obstruction, bronchial hyper responsiveness and inflammation. Asthma may be classified clinically on the basis of various … |
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Montelukast: A Review of Recent Studies in Pediatric Asthma and Allergic Rhinitis
Medscape Montelukast was approved by the Food and Drug Administration (FDA) on February 20, 1998 for the treatment of asthma in children and adults. It has gained widespread acceptance as an adjunct to inhaled corticosteroids and beta-adrenergic agonists in the … |
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Targeting Nerve Endings To Curb Allergic Asthma
PR Newswire (press release) BOSTON, June 25, 2015 /PRNewswire-USNewswire/ — Current asthma medications, which work by suppressing inflammatory signaling by immune cells or by dilating the airways, can stop working over time. A study from Boston Children's Hospital, Brigham … |
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Targeting nerve endings to curb allergic asthma
Medical Xpress Current asthma medications, which work by suppressing inflammatory signaling by immune cells or by dilating the airways, can stop working over time. A study from Boston Children's Hospital, Brigham and Women's Hospital, and Harvard Medical School … |
View full post on asthma – Google News