Asthma Risk and Bedroom chemicals – Swedish Study Reports

Recent press reports reflcet that Children are up to three times more likely to develop conditions like asthma and hayfever due to chemicals found in some wall paints and cleansers according to a recent study conducted in Sweden

Researchers from Karlstad University in Sweden found youngsters had up to 180 per cent greater risk of developing allergies if they were exposed to chemicals known as PGEs in their bedrooms.

The study looked at the effect of PGE chemicals, which are found in some wall paints and plastic toys and packaging

Study leader Professor Carl-Gustaf Bornehag, said: ‘The study shows for the first time that the concentration of PGEs, propylene glycol and glycol ethers, in bedroom air was linked to an increased risk of developing asthma, rhinitis and eczema in children.

‘The increase in risk varied between 50 and 180 per cent. It was also found that a higher concentration of PGEs in indoor air was associated with children evincing antibodies (IgE) against allergens such as cats, dogs, pollen.

‘Our analyses also revealed that the use of water-based paint in the dwelling, as well as water-based cleansers, was linked to a higher concentration of PGEs in bedroom air.’

The chemicals can also be found in some plastic toys and packaging.

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The researchers studied 198 preschool children with asthma and allergies along with 202 healthy controls in Varmland, Sweden.

Air samples were taken from the children’s bedrooms and eight groups of volatile compounds were analysed.

The children were then examined by doctors while their parents filled in a general health questionnaire about the family’s health and lifestyle.

Professor Bornehag said: ‘We have previously shown that phthalates from soft PVD could be tied to allergic conditions in children.

‘Now we have focused on PGEs. Among the substances identified are compounds suspected of disturbing hormones, which was also the case regarding the phthalates we studied earlier.’

Professor Bornehag said: ‘Our findings once again raise the question of the health-related aspects of the use of chemicals in our everyday lives.

‘Particularly when it comes to exposure in our home environments, since small children and pregnant women spend a great deal of their time there and there are many indications that exposing fetuses and infants is probably more risky.’

The scientists, whose study was published in the journal PLoS One, said further research was needed into how chemical exposure in childhood could contribute to chronic conditions.

Top Ten Fall Allergy Myths – NBC Washington


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Myth #9: Allergies and asthma are completely unrelated. In fact they're completely the same. It's one big airway whether you get the allergy up your nose or
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NIH-funded Study Finds 2.5 Percent of Americans Have a Food Allergy – Occupational Health & Safety

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NIH-funded Study: Nearly 3 of 100 Americans Have a Food Allergy – Newswise (press release)


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Antibiotics Investigated as Asthma, Allergy Cause – Discovery News


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Asthma comes first, not allergy, study finds – Sydney Morning Herald

Asthma comes first, not allergy, study finds

Press reports suggest that allergies are a consequence of asthma, not a cause of it, the largest genetic study of the condition has concluded.

Scientists have found seven genes linked to the development of the ailment, which could lead to new treatments.
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Researchers from Imperial College London and colleagues around the world carried out more than half a million genetic tests on 26,000 subjects.

The findings, published in The New England Journal of Medicine, suggest that allergies are a consequence of asthma, which causes damaged airways.

They also found that adult-onset asthma and childhood asthma were different diseases.

But the head of respiratory and environmental epidemiology at the Woolcock Institute in Sydney, Guy Marks, said he did not think the study had definitively shown that allergies were a consequence of asthma, not the cause.

”That is the conclusion the authors have drawn but I would be a bit more cautious,” he said.

He believed this type of research – including other genetic studies of asthma being conducted among Australians – might lead to better-targeted treatments and ways to prevent asthma in the first place. Australian asthma rates were among the highest in the world, said the chief executive of the Asthma Foundation NSW, Michele Goldman.

About one in nine children and one in 10 adults had it. It was thought to be caused by a combination of genetic and environmental factors, Ms Goldman said.

This research highlighted that asthmatics were better off finding a medication that worked for them than trying to avoid potential allergens, she said.

The genes were found in a third of children with asthma. Some were involved in activating the immune system; others were linked to breathing. This means treatments could be designed to correct their function.

Professor William Cookson, of Imperial College London, who co-ordinated the research, said: ”Our study highlights targets for asthma therapies and suggests that therapies against these targets will be of use to many asthmatics.”

The researchers will now look for what causes damage to the airways and why some factors seem to protect against asthma.