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Scientists to explore biology of human asthma by using slime mould
News-Medical.net Scientists from Royal Holloway, University of London, will research the biology of human asthma by using a slime mould, an organism which has no lungs but could hold the key to new treatments. Professor Robin Williams, from the School of Biological … |
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UPI.com |
Researchers find new molecule to treat asthma
Biology News Net (press release) The study, performed in mouse models for asthma research, showed that the synthetic sulfate monosaccharide blocks the interaction between chemokine CCL20—a T-cell signaling protein—and heparin sulfate, a molecule that protects and immobilizes … Synthetic molecule thwarts asthma symptoms Novel Molecule may Prevent Allergen-Induced Asthma |
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Invited Commentary: Childhood Acute Lymphoblastic Leukemia and Allergies: Biology or Bias?
Am J Epidemiol. 2012 Nov 20;
Authors: Linabery AM, Spector LG
Abstract
Previous epidemiologic studies have shown an inverse association between a personal history of atopy/allergies, both overall and among asthma, eczema, and hay fever investigated separately, and childhood acute lymphoblastic leukemia (ALL) with some consistency; however, in most of these studies, exposure data were collected by maternal interview. Now, in a population-based and records-based study in this issue of the Journal (Am J Epidemiol. 2012;000(0):000-000), Chang et al. report an increased risk for allergic conditions across different etiologic time periods, calling the former paradigm into doubt. A review of the basic biology literature shows that proposed mechanisms support either a positive or an inverse association. In light of this ambiguity, it is epidemiology’s turn to determine the direction of association.
PMID: 23171875 [PubMed – as supplied by publisher]
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