Mice at risk of asthma, allergies can fight off skin cancer – Washington University in St. Louis News


Washington University in St. Louis News

Mice at risk of asthma, allergies can fight off skin cancer
Washington University in St. Louis News
A molecule involved in asthma and allergies now has been shown to make mice resistant to skin cancer, according to scientists at Washington University School of Medicine in St. Louis. The molecule, called TSLP (thymic stromal lymphopoietin), is

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Study: popular cleaners could cause asthma, cancer – WJXT Jacksonville


Seattle Post Intelligencer

Study: popular cleaners could cause asthma, cancer
WJXT Jacksonville
Researchers at the Environmental Working Group compared the ingredients listed on the labels of 2,000 cleaning products with information from toxicity databases from government, industry and academic sources. The results are published in their Cleaners
Many cleaners contain toxic ingredients, and some green cleaners don't list Seattle Post Intelligencer (blog)

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With Topics like Obstetric Analgesia, Asthma, IBD, Anemia, Ovarian Cancer, and … – RedOrbit

With Topics like Obstetric Analgesia, Asthma, IBD, Anemia, Ovarian Cancer, and
RedOrbit
Audio-Digest Foundation, the largest independent publisher of Continuing Medical Education in the world, is releasing free written summaries of its anesthesiology, emergency medicine, family practice, gastroenterology, general surgery, internal

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Therapeutical Measures to Control Airway Tolerance in Asthma and Lung Cancer.

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Therapeutical Measures to Control Airway Tolerance in Asthma and Lung Cancer.

Front Immunol. 2012;3:216

Authors: Andreev K, Graser A, Maier A, Mousset S, Finotto S

Abstract
Airway tolerance is a specialized immunological surveillance which is activated by the cells of the lung to deal with and distinguish between innocuous and pathogenic inhalants. However, this distinction does not always occur. Airway tolerance is necessary to avoid the development of allergic disorders, such as asthma, which is dominated by a pathological expansion of Th2 and Th17 cells in the airways. By contrast, tumor cells induce tolerogenic factors in their microenvironment to evade T-cell mediated anti-tumor-immune responses. This review updates current understandings on the effect of the cytokines TGF-?, IL-10, and IL-17A on the lung immune responses to antigen, and analyzes their involvement in allergic asthma and lung cancer. The aim of the review is to evaluate where therapeutic intervention may be feasible and where it might fail. The multifunctional role of these cytokines further complicates the decision on the timing and concentration for their use as therapeutical targets. In fact, TGF-? has suppressive activity in early tumorigenesis, but may become tumor-promoting in the later stages of the disease. This dual behavior is sometimes due to changes in the cellular target of TGF-?, and to the expansion of the induced (i)-Tregs. Similarly, IL-17A has been found to elicit pro- as well as anti-tumor properties. Thus, this pro-inflammatory cytokine induces the production of IL-6 which interferes with Treg development. Yet IL-17A could promote tumor growth in conjunction with IL-6-dependent activation of Stat3. Thus, understanding the mechanisms of airway tolerance could help to improve the therapy to both, allergic asthma and lung cancer. Hereby, asthma therapy aims to induce and maintain tolerance to inhaled allergens and therapy against lung cancer tries to inhibit the tolerogenic response surrounding the tumor.

PMID: 22855687 [PubMed – as supplied by publisher]

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EWG’s Guide to Green Cleaning: Greenwashing, Cancer, Blindness, Asthma… – Eco Child’s Play


Eco Child’s Play

EWG's Guide to Green Cleaning: Greenwashing, Cancer, Blindness, Asthma
Eco Child’s Play
Some of their ingredients are known to cause cancer, blindness, asthma and other serious conditions. Others are greenwashed, meaning that they are not, as their ad hype claims, environmentally benign. Still more hide the facts about their formulations

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Invisible children – the missing victims of cancer, asthma and diabetes – The Guardian (blog)


The Guardian (blog)

Invisible children – the missing victims of cancer, asthma and diabetes
The Guardian (blog)
Children in the poorest countries die of cancer and asthma and diabetes – but the targets under consideration are to bring down the deaths of adults over the age of 30. This is what she said when I woke her up at 3am (apologies) last Friday,

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