Diagnosis Ottawa: More cases of cancer and asthma, but better heart health … – Ottawa Citizen

Diagnosis Ottawa: More cases of cancer and asthma, but better heart health
Ottawa Citizen
OTTAWA — Ottawans suffer more from cancer and asthma than other Ontarians, but our heart health is distinctly better, say reports from the city's public-health unit. Incidence rates of all cancers combined and of melanoma in particular were found to

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Asthma and COPD Treatment in the UK Could Improve Says New Study

Asthma and COPD Treatment in the UK Could Improve Says New Study by the Organisation for Economic Cooperation and Development (OECD)

The Pharma Times is reporting that survival rates for different cancers are improving in the UK, but most of the other 33 nations of the Organisation for Economic Cooperation and Development (OECD) achieve higher rates, says a new report.

Also, while the UK does well in avoiding hospital admissions for people with uncontrolled diabetes, it could improve the treatment of patients with asthma and chronic obstructive pulmonary disease (COPD), according to the OECD’s annual Health at a Glance report.

The five-year relative survival rate for breast cancer in the UK during 2004-9 was 81%, up from 75% during 1997-2002, but still lower than the OECD average of 84%, says the study. For cervical cancer the rate was 59%, also lower than the OECD average of 66%, and for colorectal cancer the UK’s five-year survival rate during 2004-9 was 54% for female patients and 53% for males, compared with an Organisation average of 62% for women and 60% for men.

Also, avoidable hospital admissions for asthma complications and COPD are higher in the UK than the OECD average; for asthma admissions the rate was 74 per 100,000 adults in 2009 (OECD average 52) and for COPD it was 213 (OECD average 198).

On the other hand, admissions in the UK for uncontrolled diabetes are less than half the OECD average, at 24 versus 50 admissions per 100,000 population.

The report also notes that in 2009, for the first time, the share of Gross Domestic Product (GDP) allocated to health in the UK exceeded the OECD average, reaching 9.8% compared with an average of 9.6%.

The share of GDP allocated to health has increased strongly in the UK over past decade, particularly during the 2008-9 recession, rising from 8.4% in 2007 to 9.8% in 2009, it comments.

UK spending on health per person in 2009 was US$3,487, adjusted for purchasing parity, which is also slightly higher than the OECD average of $3,233, and per capita spending grew 4.8% in real terms in the UK during 2000-9 (Organisation average 4%).

84% of health spending in the UK was funded by public sources in 2009, which is well above the Organisation average of 72% and among the highest share in OECD nations.

Overall, the new edition of Health at a Glance says that medical care is improving in OECD member countries, but better prevention and management of chronic diseases is needed to reduce costs.

S-Nitrosoglutathione reductase in human lung cancer.

S-Nitrosoglutathione reductase in human lung cancer.

Am J Respir Cell Mol Biol. 2011 Aug 4;

Authors: Marozkina NV, Yemen S, Wei C, Wallrabe H, Nagji AS, Liu L, Morozkina T, Jones DR, Gaston B

S-Nitrosoglutathione (GSNO) reductase regulates cell signaling pathways relevant to asthma and protects cells from nitrosative stress. Recent evidence suggests that this enzyme may prevent human hepatocellular carcinoma arising in the setting of chronic hepatitis. We hypothesized that GSNO reductase could also protect the lung against potentially carcinogenic reactions of associated with nitrosative stress. We report that wild-type Ras is S-nitrosylated and activated by nitrosative stress; and that it is denitrosylated by GSNO reductase. In human lung cancer, GSNO reductase activity and expression are decreased. Further, distribution of the enzyme – including its colocalization with wild-type Ras – is abnormal. We conclude that decreased GSNO reductase activity could leave the human lung vulnerable to the oncogenic effects of nitrosative stress, as is the case in the liver. This potential should be considered when developing therapies that inhibit pulmonary GSNO reductase to treat asthma and other conditions.

PMID: 21816964 [PubMed – as supplied by publisher]

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Allergies reduce the risk of cancer – Deccan Herald

Allergies reduce the risk of cancer
Deccan Herald
Most have found that compared with the general population, people with common allergies like hay fever, asthma and eczema do have a slightly decreased risk of some cancers, though it is not clear why. In a study published online this month in the
Study Up for a Sneeze and Wheeze-Free School YearNewswise (press release)

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Google Science Fair Winners – Treating Asthma and Cancer – Search Engine Journal


Fox News

Google Science Fair Winners – Treating Asthma and Cancer
Search Engine Journal
2011?s science fair has concluded, and the three winners all took on impressive scientific tasks that address major issues such as carcinogen intake and controlling asthma. Most impressive, the grand prize winner conducted research that made new
Google Science Fair winners announced: grilled chicken, ovarian cancer, asthma Engadget
Girls Dominate Google's Science Fair With Projects On Cancer And Asthma TreatmentFast Company
Youths tackle cancer, asthma for Google science fair (photos)CNET
Hindustan Times –CIOL –New York Times (blog)
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Youths tackle cancer, asthma for Google science fair (photos) – CNET


AFP

Youths tackle cancer, asthma for Google science fair (photos)
CNET
Lauren Hodge won the 13-14 age group for her project, which examined carcinogenic compounds found in grilled chicken; and Naomi Shah took the top prize in the 15- to 16-year-old category for her study of environmental factors contributing to asthma,
You Go, Google GirlsSlate Magazine (blog)
Google Science Fair Winners AnnouncedWebProNews
The Teenage Winners of Google's Global Science Fair [PICS]Mashable
NPR –AFP –msnbc.com
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