Breathe Well Live Well
|
Redox mechanisms in allergic asthma associated with disease pathogenesis
Healio Redox mechanisms of oxidative stress in allergic asthma played a “critical role” in disease pathogenesis and could be a therapeutic target, according to recent study results. Researchers conducted a literature review of PubMed for redox therapy … |
View full post on asthma – Google News
|
Asthma, heart disease make secondhand smoke dangerous
Worcester Telegram DEAR ANNIE: I am a nonsmoker who has asthma and early heart disease. When I am at family events and outdoor concerts or entering stores and public places, I often find myself exposed to secondhand smoke from cigarettes and cigars. Even though I make … |
View full post on asthma – Google News
|
Asthma Camp teaches kids how to manage the disease
WBXH BATON ROUGE, LA (WAFB) – How can a relay race help prevent asthma attacks? When it's part of an educational summer camp. According to the Centers for Disease Control, asthma affects nearly 7 million kids nationwide. In Baton Rouge, a city that is … |
View full post on asthma – Google News
Boston Globe |
Childhood asthma, lung disease elevated near airport, study finds
Boston Globe Children who live in neighborhoods bordering Logan International Airport are as much as four times more likely to wheeze, experience shortness of breath, and exhibit other signs of undiagnosed asthma compared to children who live farther away … Study Released On Health Impacts Of Logan Airport Health Study on Impacts of Logan Airport out Today |
View full post on asthma – Google News
| Related Articles |
Influenza vaccination in children at high risk of respiratory disease.
Ther Adv Vaccines. 2013 May;1(1):21-31
Authors: Patria MF, Tagliabue C, Longhi B, Esposito S
Abstract
Chronic respiratory diseases (CRDs) are a heterogeneous group of diseases that can affect the pediatric population and health authorities throughout the world recommend influenza vaccination because of the significant risk of influenza-related complications. However, despite this recommendation, vaccine coverage is generally unsatisfactory. The aim of this review is to analyze the impact of influenza on children at high risk of respiratory disease, and the immunogenicity, safety and efficacy of influenza vaccination in such children. The results show that there is a significant risk of influenza-related complications in preterm neonates and infants, in whom influenza vaccines are immunogenic and safe (although their efficacy has not been specifically studied). There are conflicting data concerning the effect of influenza infection on asthma morbidity in children, and whether or not influenza vaccination helps to prevent asthma exacerbations. Recent data provide no evidence that influenza is more frequent in patients with cystic fibrosis than in healthy subjects, or that it is responsible for increased lower respiratory tract morbidity. The lack of any clear correlate of protection suggests that future studies should also consider the efficacy of the different influenza vaccines and not only evaluate them in terms of immunogenicity. Furthermore, there is a need for clinical studies to assess the effectiveness of the available vaccines in patients with other rare CRDs and other chronic underlying diseases with possibly severe respiratory involvement. It is also important to determine whether children with recurrent respiratory tract infections should be included in the list of those for whom influenza vaccination is recommended. In the meantime, given the increasing evidence of the burden of influenza on the population as a whole and the benefits associated with vaccination, annual influenza vaccinations should be recommended for all children at high risk of respiratory disease and the members of their households.
PMID: 24757513 [PubMed]
View full post on pubmed: asthma
|
Asthma is common childhood disease
Central Kentucky News These symptoms may make it harder for your child to sleep, making him fatigued during the day. During an asthma attack, these symptoms intensify due to further inflammation. Asthma attacks can be stimulated by triggers such as viral infections, air … |
View full post on asthma – Google News
Condition: Pulmonary Disease, Chronic Obstructive
Interventions: Drug: Mepolizumab; Drug: Placebo
Sponsor: GlaxoSmithKline
Not yet recruiting – verified April 2014
View full post on ClinicalTrials.gov: asthma | received in the last 14 days
| Related Articles |
Respiratory syncytial virus and seasonal influenza cause similar illnesses in children with sickle cell disease.
Pediatr Blood Cancer. 2014 Jan 31;
Authors: Sadreameli SC, Reller ME, Bundy DG, Casella JF, Strouse JJ
Abstract
BACKGROUND: Respiratory syncytial virus (RSV) is a cause of acute chest syndrome (ACS) in sickle cell disease (SCD), but its clinical course and acute complications have not been well characterized. We compared RSV to seasonal influenza infections in children with SCD.
PROCEDURE: We defined cases as laboratory-confirmed RSV or seasonal influenza infection in inpatients and outpatients <18 years of age with SCD from 1 September 1993 to 30 June 2011. We used Fisher’s exact test to compare proportions, Student’s t-test or Wilcoxon rank-sum test to compare continuous variables, and logistic regression to evaluate associations.
RESULTS: We identified 64 children with RSV and 91 with seasonal influenza. Clinical symptoms, including fever, cough, and rhinorrhea were similar for RSV and influenza, as were complications, including ACS and treatments for SCD. In a multivariable logistic regression model, older age (OR 1.2 per year, 95% CI [1.02-1.5], P?=?0.04), increased white blood cell count at presentation (OR 1.1 per 1,000/?l increase, 95% CI [1.03-1.3], P?=?0.008), and a history of asthma (OR 7, 95% [CI 1.3-37], P?=?0.03) were independently associated with increased risk of ACS in children with RSV. The hospitalization rate for children with SCD and RSV (40 per 1,000 <5 years and 63 per 1,000 <2 years) greatly exceeds the general population (3 in 1,000 <5 years).
CONCLUSIONS: We conclude that RSV infection is often associated with ACS and similar in severity to influenza infection in febrile children with SCD. Pediatr Blood Cancer 2014;9999:1-4. © 2014 Wiley Periodicals, Inc.
PMID: 24481883 [PubMed – as supplied by publisher]
View full post on pubmed: asthma
|
Asthma: Disease Management Program Is Largely Consistent With Guidelines
Science Daily (press release) 22, 2014 — On 22 January 2014 the German Institute for Quality and Efficiency in Health Care (IQWiG) published the results of a literature search for evidence-based clinical practice guidelines on the treatment of people with asthma. The aim of the … |
View full post on asthma – Google News
Chronic Rhino-Sinusitis and Asthma: Concept of Unified Airway Disease (UAD) and its Impact in Otolaryngology.
Indian J Otolaryngol Head Neck Surg. 2013 Aug;65(Suppl 2):338-42
Authors: Meena RS, Meena D, Aseri Y, Singh BK, Verma PC
Abstract
The aim of our study is to understand the concept of unified airway disease, to know the advantage of this concept in the diagnosis and treatment of allergic rhinitis, chronic rhino-sinusitis and asthma, to know its impact on practice of otolaryngologists, to motivate the otorhinolaryngologist to apply this concept in diagnosis and treatment. This article is based on our experience on (20 cases) chronic rhino-sinusitis and asthma, and observations and results from various literatures. Implement of the concept of unified airway disease and ability to translate its principles into successful diagnostic and treatment strategies can enhance the practice of otolaryngology. The end result is the potential for improved patient care. In our study 80% cases have reduced frequency of symptoms and all (100%) cases having improved night time symptoms thus the use of short-acting beta2 agonist to control the asthma symptoms decreases.
PMID: 24427673 [PubMed]
View full post on pubmed: asthma