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Elevated blood eosinophil levels are a risk factor for asthma exacerbations
Medical Xpress In adults with persistent asthma, elevated blood eosinophil levels may be able to predict which individuals are at increased risk for exacerbations, according to a new study presented at the 2014 American Thoracic Society International Conference. |
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Obese asthma patients at risk for seasonal exacerbations
medwireNews medwireNews: Research shows that overweight and obese patients with asthma have an increased risk for exacerbations, particularly in the fall and winter. Study authors Michael Schatz (Kaiser Permanente Medical Center, San Diego, California, USA) and … |
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Hypereosinophilic syndrome secondary to strongyloides infection: a case of recurrent asthma exacerbations.
BMJ Case Rep. 2013;2013
Authors: Khan WA, Santhanakrishnan K
Abstract
Hypereosinophilic syndrome is a disease characterised by a persistently elevated eosinophil count. The syndrome can be reactive to infections, autoimmune disease, cancers, etc. Multiple organ involvement can occur including cardiomyopathies, pulmonary involvement and neuropathies. We describe a case of a patient who presented with signs and symptoms of asthma with recurrent asthma exacerbations, but in fact proved to be hypereosinophilic syndrome secondary to strongyloides infection.
PMID: 23964035 [PubMed – in process]
View full post on pubmed: asthma
Condition: Asthma
Intervention: Dietary Supplement: Cholecalciferol
Sponsors: University of Pittsburgh; University of Pittsburgh
Recruiting – verified August 2013
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Day-to-day measurement of patient-reported outcomes in exacerbations of chronic obstructive pulmonary disease.
Int J Chron Obstruct Pulmon Dis. 2013;8:273-86
Authors: Kocks JW, van den Berg JW, Kerstjens HA, Uil SM, Vonk JM, de Jong YP, Tsiligianni IG, van der Molen T
Abstract
BACKGROUND: Exacerbations of chronic obstructive pulmonary disease (COPD) are a major burden to patients and to society. Little is known about the possible role of day-to-day patient-reported outcomes during an exacerbation. This study aims to describe the day-to-day course of patient-reported health status during exacerbations of COPD and to assess its value in predicting clinical outcomes.
METHODS: Data from two randomized controlled COPD exacerbation trials (n = 210 and n = 45 patients) were used to describe both the feasibility of daily collection of and the day-to-day course of patient-reported outcomes during outpatient treatment or admission to hospital. In addition to clinical parameters, the BORG dyspnea score, the Clinical COPD Questionnaire (CCQ), and the St George’s Respiratory Questionnaire were used in Cox regression models to predict treatment failure, time to next exacerbation, and mortality in the hospital study.
RESULTS: All patient-reported outcomes showed a distinct pattern of improvement. In the multivariate models, absence of improvement in CCQ symptom score and impaired lung function were independent predictors of treatment failure. Health status and gender predicted time to next exacerbation. Five-year mortality was predicted by age, forced expiratory flow in one second % predicted, smoking status, and CCQ score. In outpatient management of exacerbations, health status was found to be less impaired than in hospitalized patients, while the rate and pattern of recovery was remarkably similar.
CONCLUSION: Daily health status measurements were found to predict treatment failure, which could help decision-making for patients hospitalized due to an exacerbation of COPD.
PMID: 23766644 [PubMed – in process]
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Improved clinician access, private insurance reduced asthma exacerbations
Healio Auger KA. Pediatrics. 2012;doi:10.1542/peds.2012-1055. December 26, 2012. Children with access to a medical home and private insurance were least likely to require readmission to the hospital for their asthma, according to study findings published online. |
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New drug can prevent exacerbations of asthma due to common cold: Trial report
News-Medical.net By Dr Ananya Mandal, MD For the tens of thousands of asthma sufferers in the UK there is a “breakthrough” drug that reduces complications caused by the common cold, it is claimed. Severe symptoms due to cold infections are one of the chief reasons why … Synairgen's 'breakthrough' asthma drug shines in Phase II trial Earlier trial with an unlicensed drug shows good relief in Asthma complications Scientists Hail Asthma Drug That 'Prevents Life-Threatening Symptoms' |
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Procalcitonin vs Clinical and Chest Film Findings to Diagnose Community-Acquired Pneumonia in Patients With Acute Asthma or Acute Exacerbations of Chronic Bronchitis.
Chest. 2011 Dec;140(6):1667-8
Authors: Cunha BA
PMID: 22147830 [PubMed – in process]
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Asthma Exacerbations Can Last a Week or Longer
Medscape November 13, 2011 (Boston, Massachusetts) — Episodes of asthma worsening, when symptoms become more severe or frequent, commonly last for a week or more and can seriously affect a patient's quality of life, according to a study presented in a poster … |
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New Treatment Helps Reduce Asthma Exacerbations During Pregnancy
Medical News Today To help reduce asthma exacerbations during pregnancy, a new treatment algorithm has been designed by investigators in Australia. The article is written by Professor Peter Gibson and Heather Powell, Centre for Asthma and Respiratory Diseases, … Better asthma treatment for mums-to-be Breakthrough for pregnant asthma sufferers Asthma management breakthrough for pregnant women |
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