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Forced oscillometry bested spirometry in detecting airway function in asthma …
Healio Although spirometry is common in assessing airway function in bronchial asthma, this method has limitations, according to Manal Refaat Hafez, MD, of the chest department at Al-Azhar University in Cairo, Egypt, and colleagues. They therefore sought to … |
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News-Medical.net |
Prediagnostic lung function impairment common in older asthma patients
News-Medical.net Older adults with newly diagnosed asthma are not only more likely to have pre-existing lung function impairment than younger adults, but they also experience a more rapid decline of lung function, a Danish team reports in Respiratory Medicine. “Our … |
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Asthma Severity and Lung Function Effectively Assessed with Dynamic Oxygen …
Lung Disease News sem nome A new study assessed the feasibility and reproducibility of dynamic oxygen-enhanced magnetic resonance imaging (OE-MRI) as a non-invasive, non-ionizing imaging technique with the capability to assess regional lung function in asthma. |
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Clinical assessment of speech correlates well with lung function during induced bronchoconstriction.
NPJ Prim Care Respir Med. 2015;25:15006
Authors: Tayler N, Grainge C, Gove K, Howarth P, Holloway J
Abstract
Clinical assessment of asthma often includes a crude assessment of speech, for example whether the patient can speak in full sentences. To date, this statement, despite appearing in national asthma guidelines, has not been related to lung function testing in asthma exacerbation. Seven asthmatics underwent a bronchial challenge and were then recorded reading a standardised text for 1?min. The recordings were played to 88 healthcare professionals who were asked to estimate FEV1% predicted. Health care professionals’ estimations showed moderate correlation to FEV1% predicted (rho=0.61 P<0.01). There were no significant differences between professionals grouped by seniority or speciality. Speech can intuitively be estimated by health care professionals with moderate accuracy. This gives an evidence basis for the assessment in speech in acute asthma and may provide a new avenue for monitoring.
PMID: 25719976 [PubMed – in process]
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New Phase III Data in Asthma Patients Show Tiotropium Improves Lung Function …
PR Newswire (press release) HOUSTON, Feb. 21, 2015 /PRNewswire/ — Boehringer Ingelheim today presented data on investigational tiotropium delivered via Respimat® inhaler from five Phase III trials from the UniTinA-asthma® program at the 2015 American Academy of Allergy, … |
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Related Articles |
Iron Status is Associated with Asthma and Lung Function in US Women.
PLoS One. 2015;10(2):e0117545
Authors: Brigham EP, McCormack MC, Takemoto CM, Matsui EC
Abstract
BACKGROUND: Asthma and iron deficiency are common conditions. Whether iron status affects the risk of asthma is unclear.
OBJECTIVE: To determine the relationship between iron status and asthma, lung function, and pulmonary inflammation.
METHODS: Relationships between measures of iron status (serum ferritin, serum soluble transferrin receptor (sTfR), and sTfR/log10ferritin (sTfR-F Index)) and asthma, lung function, and pulmonary inflammation were examined in women 20-49 years in the National Health and Nutrition Examination Survey. Logistic, linear, and quadratic regression models accounting for the survey design of NHANES were used to evaluate associations between iron status and asthma-related outcomes and were adjusted for race/ethnicity, age, smoking status, income, and BMI.
RESULTS: Approximately 16% reported a lifetime history of asthma, 9% reported current asthma, and 5% reported a recent asthma episode/attack (n = 2906). Increased ferritin (iron stores) was associated with decreased odds of lifetime asthma, current asthma, and asthma attacks/episodes in the range of ferritin linearly correlated with iron stores (20-300ng/ml). The highest quintile of ferritin (>76 ng/ml) was also associated with a decreased odds of asthma. Ferritin levels were not associated with FEV1. Increased values of the sTfR-F Index and sTfR, indicating lower body iron and higher tissue iron need, respectively, were associated with decreased FEV1, but neither was associated with asthma. None of the iron indices were associated with FeNO.
CONCLUSION: In US women, higher iron stores were inversely associated with asthma and lower body iron and higher tissue iron need were associated with lower lung function. Together, these findings suggest that iron status may play a role in asthma and lung function in US women.
PMID: 25689633 [PubMed – as supplied by publisher]
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Related Articles |
Effect of indoor nitrogen dioxide on lung function in urban environment.
Environ Res. 2015 Feb 12;138C:8-16
Authors: Cibella F, Cuttitta G, Della Maggiore R, Ruggieri S, Panunzi S, De Gaetano A, Bucchieri S, Drago G, Melis MR, La Grutta S, Viegi G
Abstract
BACKGROUND: High levels of indoor NO2 are associated with increased asthma symptoms and decreased expiratory peak flows in children. We investigated the association of exposure to domestic indoor NO2, objectively measured in winter and spring, with respiratory symptoms and lung function in a sample of adolescents from a southern Mediterranean area.
METHODS: From a large school population sample (n=2150) participating in an epidemiological survey in the urban area of the City of Palermo (southern Italy), a sub-sample of 303 adolescents was selected which furnished an enriched sample for cases of current asthma. All subjects were evaluated by a health questionnaire, skin prick tests and spirometry. One-week indoor NO2 monitoring of their homes was performed by diffusive sampling during spring and again during winter.
RESULTS: We found that about 25% of subjects were exposed to indoor NO2 levels higher than the 40µg/m(3) World Health Organization limit, during both spring and winter. Moreover, subjects exposed to the highest indoor NO2 concentrations had increased frequency of current asthma (p=0.005), wheeze episodes in the last 12 months (p<0.001), chronic phlegm (p=0.013), and rhinoconjunctivitis (p=0.008). Finally, subjects with a personal history of wheeze ever had poorer respiratory function (FEF25-75%, p=0.01) when exposed to higher indoor NO2 concentrations.
CONCLUSIONS: Home exposure to high indoor NO2 levels frequently occurs in adolescents living in a southern Mediterranean urban area and is significantly associated with the risks for increased frequency of both respiratory symptoms and reduced lung function.
PMID: 25682253 [PubMed – as supplied by publisher]
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Science Codex |
Asthma patients reduce symptoms and improve lung function with shallow …
Science Codex The results suggest asthma patients using behavioral therapy in conjunction with their daily asthma medicine can improve their lung health over the long-term, said principal investigators Thomas Ritz and Alicia E. Meuret, both SMU clinical psychologists. |
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Medical Xpress |
Asthma patients reduce symptoms, improve lung function with shallow breaths …
Medical Xpress The results suggest asthma patients using behavioral therapy in conjunction with their daily asthma medicine can improve their lung health over the long-term, said principal investigators Thomas Ritz and Alicia E. Meuret, both SMU clinical psychologists. |
View full post on asthma – Google News
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Reduced lung function in infancy linked to asthma at age 8
Healio Physician-diagnosed asthma was present in 39 children (83%), current asthma in 25 (53%) and past asthma in 14 (30%). Ongoing asthma symptoms were observed in 27 (57%) children, seven (15%) of whom presented with ongoing wheeze. Of the patients … |
View full post on asthma – Google News