Determinants of longitudinal health-related quality of life change in children with asthma from low-income families: a report from the PROMIS(®) Pediatric Asthma Study.

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Determinants of longitudinal health-related quality of life change in children with asthma from low-income families: a report from the PROMIS(®) Pediatric Asthma Study.

Clin Exp Allergy. 2016 Sep 24;

Authors: Li Z, Leite W, Thompson L, Gross HE, Shenkman E, Reeve BB, DeWalt DA, Huang IC

Abstract
BACKGROUND: How the longitudinal asthma control status and other socio-demographic factors influence the changes of health-related quality of life (HRQOL) among asthmatic children, especially from low-income families, has not been fully investigated.
OBJECTIVES: This study aimed to describe the trajectories of asthma-specific HRQOL over 15 months, and examine the effect of asthma control status on HRQOL by taking socio-demographic factors into consideration.
METHODS: 229 dyads of asthmatic children and their parents enrolled in public insurance programs were recruited for assessing asthma control status and HRQOL over 4 time points of assessment. Asthma control status was measured using the Asthma Control and Communication Instrument and asthma-specific HRQOL was assessed using the Patient-Reported Outcomes Measurement Information System’s Pediatric Asthma Impact Scale. Latent growth models (LGMs) were applied to examine the trajectory of HRQOL and the factors contributing to the changes of HRQOL.
RESULTS: Unconditional LGM revealed that HRQOL was improved over time. Conditional LGM suggested that accounting for asthma control and participants’ socio-demographic factors, the variation in the initial level of HRQOL was significant, yet the rate of change was not. Conditional LGM also revealed that poorly-controlled asthma status was associated with poor HRQOL at each time point (p’s<0.05). Lower parental education was associated with lower baseline HRQOL (p<0.05). Hispanic children had a larger increase in HRQOL over time (p<0.01) than non-Hispanic White children.
CONCLUSIONS: Vulnerable socio-demographic characteristics and poorly controlled asthma status affect HRQOL in children. This finding encourages interventions to improve asthma control status and HRQOL in minority children. This article is protected by copyright. All rights reserved.

PMID: 27664979 [PubMed – as supplied by publisher]

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UMass Memorial Health Care Receives National Award for Pediatric Asthma Program – GoLocal Worcester

UMass Memorial Health Care Receives National Award for Pediatric Asthma Program
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In 2014, UMass Memorial Children's Medical Center expanded a pilot program for children with poorly controlled asthma. Under the program, when a clinician or school nurse identifies a child as high risk asthmatic, a specially trained community health …

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MD Magazine

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The research team used the Expert Panel Report 3 (EPR-3): Guidelines for the Diagnosis and Management of Asthma, and requested that clinicians ask patients five standardized questions regarding their asthma symptoms and use of rescue medication.

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Where does current and future pediatric asthma treatment stand? Remodeling and inflammation: Bird’s eye view.

Where does current and future pediatric asthma treatment stand? Remodeling and inflammation: Bird’s eye view.

Pediatr Pulmonol. 2016 May 27;

Authors: Yilmaz O, Yuksel H

Abstract
Airway remodeling is the chronic outcome of inflammation in asthma and a point of intervention between pediatric and adult ages. Pediatric asthma has been of great interest in the efforts to find a valuable time to interrupt remodeling. Various experimental and clinical research have assessed the effect of current therapeutic modalities on airway remodeling in asthma and many new agents are being developed with promising results. The heterogeneity in the results of these studies may lie in the heterogeneity of pathogenesis leading to asthma and remodeling; underlying the need for individualized treatment of the unique pathogenetic characteristics of each child’s asthma. The aim of this review is to summarize the evidence about the influence of current and future therapeutic modalities in the concept of inflammation and remodeling in pediatric asthma. Pediatr Pulmonol. 2016; 9999:1-9. © 2016 Wiley Periodicals, Inc.

PMID: 27233079 [PubMed – as supplied by publisher]

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Miller Children’s receives top honor for Excellence in Pediatric Asthma – Orange County Breeze


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Miller Children's & Women's Hospital Long Beach became the first free-standing children's hospital in California, and only the 11th children's hospital in the nation, to receive the Disease Specific Certification in Pediatric Asthma from The Joint

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Dr. Robert Strunk, pediatric allergist and childhood asthma expert, dies at 73 – STLtoday.com


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