New Study: Overuse of Combination Drug Therapy in Patients with Mild Asthma … – PR Newswire (press release)

New Study: Overuse of Combination Drug Therapy in Patients with Mild Asthma
PR Newswire (press release)
"This study confirms that, based on pharmacy and medical claims, patients with mild asthma using only an inhaled corticosteroid seem to control their asthma
ICS/LABA combination therapy increases asthma-related pharmacy costNews-Medical.net

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Cinryze® (C1 esterase inhibitor [human]) Data Presented at 2010 Annual Meeting … – PR Newswire (press release)

Cinryze® (C1 esterase inhibitor [human]) Data Presented at 2010 Annual Meeting
PR Newswire (press release)
There can be no assurance that that the data presented during the 2010 Annual Meeting of the American College of Allergy, Asthma & Immunology (ACAAI)
Cinryze(R) (C1 esterase inhibitor [human]) Data Presented at 2010 Annual Investor’s Business Daily

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Combatting Asthma – New task force Assembled

New task force assembled at University of Leicester to Combat Asthma

A new task force for combating asthma in Leicester is being spearheaded by a University of Leicester medical researcher.

Dr Monica Lakhanpaul, Senior Lecturer in Child Health and Consultant Community Paediatrician and her co-researchers, have won a grant from the NIHR Health Services Research programme to work with the community, families, children and professionals to develop a tailored management and intervention programme for asthma in South Asian children in Leicester.

The team will be interviewing members of the community, children with asthma and their parents to give them a voice in academic and clinical forums, so that the end product interventions are informed by the views and experiences of people who suffer with asthma and who live with asthma patients.

“This means we will be developing services with the community for the community,” said Dr Lakhanpaul. “The research will serve as a model for working collaboratively to develop community health care programmes across the UK – for all communities.”

Dr Lakhanpaul said: “Asthma is one of the most common long-term childhood conditions, affecting 1 in 11 children in the UK. South Asian children with asthma suffer poorer health and outcomes than others.

“On completion, our research will provide evidence to be used when tailoring and delivering intervention programmes by providing a template for child, family, community and professional collaboration in intervention design that is intended to be transferrable to children with other chronic conditions or from other population groups.

The study will explore the perceptions and experiences of parents and children, the attitudes and experiences of the wider community in relation to child health and those of healthcare professionals involved in commissioning or delivering services for children and families.”

An important feature about the study is how it brings together researchers in the medical field with social scientists and psychologists to work together.

Dr Lakhanpaul will lead a team from the University of Leicester, De Montfort University, Leicester City Primary Care Trust and University Hospitals of Leicester NHS Trust in order to work with South Asian children, adults and healthcare professionals to understand the problem and find solutions.

Her co-researchers are:

Deborah Bird, Clinical Research Fellow on the project, University of Leicester; Lorraine Culley, Professor of Social Science and Health, De Montfort University; Jonathon Grigg, Professor, Queen Mary University London; Narynder Johal, Parent Representative ; Mark Johnson, Professor of Diversity in Health and Social Care, De Montfort University; Mel McFeeters, Consultant Nurse for Children’s Respiratory Disease, University Hospitals of Leicester NHS Trust; Noelle Robertson,Senior Lecturer in Clinical Psychology and Research Director D Clin Psy, University of Leicester and Joanne Wilson, Paediatric Advanced Nurse Practitioner, Leicester City Primary Care Trust

Dr Lakhanpaul said: “In Leicester, a multi-cultural city with a 30% South Asian population, the rate of admission per 100,000 children was found to be 4.6 times higher in South Asian children than other children. One suggestion is that South Asian children are being under-diagnosed and under-treated at home and in the community, which may explain the increased use and need for hospital care.”

The Management and Interventions for Asthma Study (MIA) will develop suggestions for improving access to, and use of, services and ways of increasing success and confidence in self-management of asthma amongst South Asian communities.

Dr Lakhanpaul said: “MIA’s strength comes from its collaborative approach to research: it is hoped that by working with children, families and professionals, the study will be kept focussed on the issues that are important to the people affected by asthma and that the solutions are both practical and appropriate.

The lessons learnt from the study will help others to work collaboratively with communities to identify health issues which are of concern to them and to develop improved ways of tackling these.

Allergic to Bed Bugs? Allergists Detect, Treat Often Overlooked Bites – Newswise (press release)


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KALBITOR(R) (ecallantide) Data Presented at the American College of Allergy … – MarketWatch (press release)

KALBITOR(R) (ecallantide) Data Presented at the American College of Allergy
MarketWatch (press release)
Ecallantide for Treatment of Acute Attacks of Acquired C1 Esterase Inhibitor Deficiency — Nisha S. Patel, MD, Asthma Allergy & Pulmonary Associates,
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Chinese Herbs Can Complement Proven Allergy Treatments Herbal Formula Shows … – Newswise (press release)

Chinese Herbs Can Complement Proven Allergy Treatments Herbal Formula Shows
Newswise (press release)
Newswise — Complementary and alternative medicine may give allergy and asthma sufferers new options for treating symptoms, according to allergists at the
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NIAID media tipsheet: Annual Meeting of the American College of Allergy … – EurekAlert (press release)

NIAID media tipsheet: Annual Meeting of the American College of Allergy
EurekAlert (press release)
WHAT: The 2010 Annual Meeting of the American College of Allergy, Asthma & Immunology (ACAAI) brings together leading allergists and immunologists from
World Allergy Organization hosts inaugural international scientific conference Trading Markets (press release)
NIAID media tipsheet: Annual Meeting of the American College of Allergy ScienceBlog.com (blog)

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Research and Markets: Asthma: Modern Therapeutic Targets

Research and Markets: Asthma: Modern Therapeutic Targets

Research and Markets has announced the addition of the “Asthma: Modern Therapeutic Targets” book to their offering.

The care of an increasing number of adult and child patients with asthma has become a major task for clinicians, and a growing concern for public health physicians and health care administrators. At the same time, and in response to this situation, a considerable effort is being made in basic and clinical research to develop new treatments. This book looks into the future and assesses the possibilities of a number of new therapies for asthma under exploration and development. A group of distinguished international authors examine the potential of new agents working on various targets that are currently under evaluation, including autocoids and their inhibitors, enzyme-inhibitors, sensory nerves and sensory neuropeptides, and receptors in immunology Asthma: Modern Therapeutic Targets provides physicians with an appreciation of the future directions of treatment. It provides clinical pharmacologists and researchers with an up-to-date insight into advances in this exciting field. This book will also be a valuable tool for researchers in the pharmaceutical industry.

Benefits:

* Presents a comprehensive review of current treatment options
* Latest guidelines on clinical management reviewed from an international perspective
* Provides background on pharmacology and mechanisms of drug action
* Provides a key resource for individual patient care

Readership:

* Specialists in respiratory medicine, allergy and immunology
* General physicians
* Clinical pharmacologists
* Doctors in training

Key Topics Covered:

Section I: Autocoids and their receptors in airway diseases

* Adenosine receptors: novel molecular targets in asthma
* The role of transforming growth factors in asthma and their potential as a target for therapy
* The role of transcription factors in asthma: can we modify them for therapeutic purposes?
* Is IKK a feasible therapeutic target for allergic asthma?

Section II: Enzyme inhibitors

* Protease-activated receptors: targets for therapeutic intervention in asthma
* Nitric oxide synthase as a therapeutic target in asthma
* Metalloproteinases and asthma: untried potential for new therapeutic strategies

Section III: Sensory nerves and sensory neuropeptides

* Sensory neuropeptides as innovative targets in asthma
* Rationale for vanilloid receptor 1 antagonist-based therapies in asthma

Section IV: Receptors in immunology

* Anticytokines and cytokines as asthma therapy
* Tumour necrosis factor alpha and asthma
* Are chemokines viable targets for asthma?
* Antagonism of the chemokine receptor CCR3 as a potential therapeutic treatment for asthma

Author:

* R Polosa, Presidio Ospedaliero Ascoli-Tomaselli, Catania, Italy
* ST Holgate, Southampton General Hospital, Southampton, UK

For more information visit http://www.researchandmarkets.com/research/a7c5bf/asthma_modern_the

Contacts

Research and Markets
Laura Wood, Senior Manager,
press@researchandmarkets.com
U.S. Fax: 646-607-1907
Fax (outside U.S.): +353-1-481-1716