Diagnosing Respiratory Disease in Children Using Cough Sounds

Conditions:   Pneumonia;   Bronchiolitis;   Asthma;   Croup;   Upper Respiratory Tract Infection;   Lower Respiratory Tract Infection
Intervention:   Other: Recording of Infants and Children’s Cough Sounds
Sponsors:   ResApp Health Limited;   Massachusetts General Hospital;   The Cleveland Clinic;   Texas Children’s Hospital
Not yet recruiting – verified November 2016

View full post on ClinicalTrials.gov: asthma | Studies received in the last 14 days

[Specific antibody deficiency: Primary immunodeficiency associated to respiratory allergy].

Related Articles

[Specific antibody deficiency: Primary immunodeficiency associated to respiratory allergy].

Rev Chil Pediatr. 2016 Sep 7;

Authors: Fernández F, Campillay R, Palma V, Norambuena X, Quezada A

Abstract
INTRODUCTION: Specific antibody deficiency (SAD) with normal immunoglobulin and normal B cells is a primary immunodeficiency characterized by reduced ability to produce antibodies to specific antigens especially polysaccharides.
OBJECTIVE: To describe the characteristics of patients diagnosed with SAD emphasizing the association between primary immunodeficiency and allergic diseases.
PATIENTS AND METHOD: Descriptive study showing patients with SAD treated at a public hospital between August 2007 and July 2015. Other secondary or primary immunodeficiency was discarded. The diagnosis of SAD was based on recurrent infections and abnormal response to pneumococcal polysaccharide vaccine assessed by specific IgG to 10 pneumococcal serotypes.
RESULTS: Twelve patients were included, 4 males, mean age 6 years, recurrent pneumonia predominated (91.7%) as well as other respiratory and invasive infections. All patients with SAD had associated asthma, 11 had allergic rhinitis, and other allergies. Three patients did not respond to any of the 10 serotypes contained in pneumococcal polysaccharide vaccine, and those who responded were with low titers. Treatment with conjugate pneumococcal vaccine was favorable in 11/12 patients.
CONCLUSION: In children older than 2 years with recurrent respiratory infections or invasive S. pneumoniae infections with normal immunoglobulin we recommend to investigate SAD, especially if they have a concurrent allergic disease.

PMID: 27614984 [PubMed – as supplied by publisher]

View full post on pubmed: asthma

Using Technology to Affect Influenza Vaccine Coverage Among Children With Chronic Respiratory Conditions.

Using Technology to Affect Influenza Vaccine Coverage Among Children With Chronic Respiratory Conditions.

J Pediatr Health Care. 2016 Jul 27;

Authors: Bay SL, Crawford DJ

Abstract
INTRODUCTION: Influenza presents additional burdens for children with chronic respiratory conditions. Influenza vaccinations may reduce complications, yet approximately half of children remain unprotected. Evidence supports integration of text and e-mail into multicomponent strategies to increase influenza vaccination rates among children with chronic respiratory conditions.
METHODS: A single text and e-mail message was sent to those with enabled preferences in the patient portal. A follow-up survey assessed aspects of message receipt. Surveys were completed without collection of demographics.
RESULTS: A total of 3,206 messages were successfully delivered. Surveys were initiated by 107 recipients. Frequency analysis showed that text and e-mail messages were preferred forms of communication. A statistically significant relationship was found between receiving a message and receiving an influenza vaccination (p = .027).
DISCUSSION: Text and e-mail messaging are cost effective and well received, and they can be easily integrated into existing systems. These methods are translatable across populations and can convey various types of messages.

PMID: 27475928 [PubMed – as supplied by publisher]

View full post on pubmed: asthma

Differential respiratory health effects from the 2008 northern California wildfires: A spatiotemporal approach.

Differential respiratory health effects from the 2008 northern California wildfires: A spatiotemporal approach.

Environ Res. 2016 Jun 15;150:227-235

Authors: Reid CE, Jerrett M, Tager IB, Petersen ML, Mann JK, Balmes JR

Abstract
We investigated health effects associated with fine particulate matter during a long-lived, large wildfire complex in northern California in the summer of 2008. We estimated exposure to PM2.5 for each day using an exposure prediction model created through data-adaptive machine learning methods from a large set of spatiotemporal data sets. We then used Poisson generalized estimating equations to calculate the effect of exposure to 24-hour average PM2.5 on cardiovascular and respiratory hospitalizations and ED visits. We further assessed effect modification by sex, age, and area-level socioeconomic status (SES). We observed a linear increase in risk for asthma hospitalizations (RR=1.07, 95% CI=(1.05, 1.10) per 5µg/m(3) increase) and asthma ED visits (RR=1.06, 95% CI=(1.05, 1.07) per 5µg/m(3) increase) with increasing PM2.5 during the wildfires. ED visits for chronic obstructive pulmonary disease (COPD) were associated with PM2.5 during the fires (RR=1.02 (95% CI=(1.01, 1.04) per 5µg/m(3) increase) and this effect was significantly different from that found before the fires but not after. We did not find consistent effects of wildfire smoke on other health outcomes. The effect of PM2.5 during the wildfire period was more pronounced in women compared to men and in adults, ages 20-64, compared to children and adults 65 or older. We also found some effect modification by area-level median income for respiratory ED visits during the wildfires, with the highest effects observed in the ZIP codes with the lowest median income. Using a novel spatiotemporal exposure model, we found some evidence of differential susceptibility to exposure to wildfire smoke.

PMID: 27318255 [PubMed – as supplied by publisher]

View full post on pubmed: asthma

Impact of a pharmacist-led asthma and COPD respiratory clinic in general practice – The Pharmaceutical Journal

Impact of a pharmacist-led asthma and COPD respiratory clinic in general practice
The Pharmaceutical Journal
Asthma and chronic obstructive pulmonary disease (COPD) continue to account for a large burden of disease in the UK. Despite comprehensive guidelines, more than 1,000 people die from asthma each year and COPD accounts for a leading cause of …

View full post on asthma – Google News

Pollution levels linked to asthma and respiratory illness – KALB News (press release)


KALB News (press release)

Pollution levels linked to asthma and respiratory illness
KALB News (press release)
WASHINGTON (AP) – The Republican-controlled House has taken aim again at President Barack Obama's environmental agenda. The House has approved a bill delaying an Obama administration rule setting stricter limits on air pollution linked to asthma …

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