New Cell Type with a Key Role in Treatment-Resistant Asthma Discovered – news Stories


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New Cell Type with a Key Role in Treatment-Resistant Asthma Discovered
news Stories
Researchers from the University of Michigan (UM) Health System have discovered a new type of cell in mice that appears to be crucial to causing asthma symptoms—even in the presence of steroid. Their findings, published in the journal Nature Medicine,
Cell as target for tough-to-treat asthmaFuturity: Research News

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Scientists discover new type of cell with a key role in treatment-resistant asthma – MarketWatch (press release)

Scientists discover new type of cell with a key role in treatment-resistant asthma
MarketWatch (press release)
For most people with asthma, a couple of puffs from an inhaler filled with steroids makes breathing easy. But if their lungs become resistant to the calming effect of that medicine, they live in fear of severe asthma attacks that could send them to the

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Scientists discover new type of cell with a key role in treatment-resistant asthma – University of Michigan Health System News (press release)


University of Michigan Health System News (press release)

Scientists discover new type of cell with a key role in treatment-resistant asthma
University of Michigan Health System News (press release)
For most people with asthma, a couple of puffs from an inhaler filled with steroids makes breathing easy. But if their lungs become resistant to the calming effect of that medicine, they live in fear of severe asthma attacks that could send them to the

and more »

View full post on asthma – Google News

Fat Hormone May Play Role in Adult Asthma – MedPage Today


MedPage Today

Fat Hormone May Play Role in Adult Asthma
MedPage Today
This study found that women with low levels of the hormone adiponectin, derived from visceral fat, may be more likely to develop adult-onset asthma. Note that low serum adiponectin was a stronger predictor of asthma incidence than was BMI.
Adiponectin Levels in Women May Predict Asthma RiskMedscape
Low Serum Adiponectin Levels Predict Future Asthma Risk in WomenNewswise (press release)
Adiponectin level link to asthmaOnMedica

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Airway Smooth Muscle Layer Has Key Role in Asthma – MD News (press release)


MD News (press release)

Airway Smooth Muscle Layer Has Key Role in Asthma
MD News (press release)
Although extracellular matrix expression in the airway smooth muscle layer is not different for patients with asthma and controls, it is associated with the dynamics of airway function in patients with asthma, according to a study published online Jan.

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Work in cells, animals, patients reveals toxin’s role in asthma – PhysOrg.com (press release)


PhysOrg.com (press release)

Work in cells, animals, patients reveals toxin's role in asthma
PhysOrg.com (press release)
Dr. Baseman leads studies of whether a common respiratory bacterial pathogen and the toxin it makes are initiating and intensifying asthma and other allergic diseases. Credit: UT Health Science Center San Antonio Five years ago, microbiologists at The

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Severity Predictors in Eschar-Positive Scrub Typhus and Role of Serum Osteopontin.

Severity Predictors in Eschar-Positive Scrub Typhus and Role of Serum Osteopontin.

Am J Trop Med Hyg. 2011 Nov;85(5):924-930

Authors: Park SW, Lee CS, Lee CK, Kwak YG, Moon C, Kim BN, Kim ES, Kang JM, Oh MD

Abstract
Abstract. We prospectively evaluated severity predictors in terms of host, microorganism, and treatment factors in 153 eschar-positive scrub typhus patients. Severity was assessed with the Acute Physiology and Chronic Health Evaluation (APACHE) II score (< 10 versus ? 10) and predefined criteria of severe complications. Genotypes of Orientia tsutsugamushi were determined. Independent risk factors for severity (APACHE II score ? 10) were old age, diabetes mellitus, serum osteopontin > 100 ng/mL, and a group of underlying diseases (congestive heart failure, cerebrovascular disease, chronic liver disease, bronchial asthma, and chronic obstructive lung diseases). Anemia (? 10 g/dL) and C-reactive protein > 10 mg/dL were indicators of current severity. Neither the delay in antibiotics administration nor strain types (Boryong, Taguchi, or Kanda/Kawasaki) contributed to the severity. The risk factors for severe complications were similar. Serum osteopontin > 100 ng/mL had a negative predictive value of 96% for severe complications. This marker can be used to rule out severe disease status.

PMID: 22049051 [PubMed – as supplied by publisher]

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