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[Severe bronchial asthma].
Ned Tijdschr Geneeskd. 2013;157(33):A6117
Authors: Toutenhoofd P, van der Zee JS
Abstract
– The term ‘difficult-to-treat asthma’ indicates that the asthma is not sufficiently controlled despite prescription of high doses of asthma medication.- The term ‘severe asthma’ is used when the asthma is still insufficiently controlled after exclusion or treatment of any complicating factors; an important complicating factor is poor compliance.- Recent studies have focused on the heterogeneous character of asthma and on the definition of specific phenotypes, with the aim of developing phenotype-specific treatments.- Treatment options for severe asthma are only partly evidence based.- The decision to implement additional therapy for severe asthma depends on the individual patient, the asthma phenotype, and the adverse-event profile of the treatment.- Many of the additional therapies should be given as a trial treatment under strict control, especially when efficacy has not been convincingly scientifically proven.
PMID: 23945432 [PubMed – in process]
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